RetrogeneDB ID: retro_ogar_2826

Retrocopy location

• Organism: Bushbaby (Otolemur garnettii)
• Coordinates: GL873668.1:4557994..4558662(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MPPE1
• Ensembl ID: ENSOGAG00000007068
• Aliases: None
• Description: metallophosphoesterase 1 [Source:HGNC Symbol;Acc:15988]

Sequence

>retro_ogar_2826
AAGGCATGGGCAGATGATGTAGAGCGGTTTCAGAAAATGTTCAGACATCCAGGTCATGTGCAGCTGAAGGTAGTTGCTGG
CAATCATGACATTGGCTTCCATTATGAGATGACCACTTATAAAATAAAATGGTTTGAGAAAATCCTCAGTTCTGAAAGGC
TGTTTTCATGGAAAGGAATTAATTTCGTGATGATTAACAGTATGGTGCCGGAAGGGGACCGTTGCATCCCCTGTTCCAAA
GCAGAAGCAGAGCTCATTGCAATTTCCCACAGACTGAACTGCTCCCGGGAGGAGCCTGCTTCCCACCAGTGTGGAGAGGG
ACAGCCATTCCTGTGTCTGCACCTGTCCTCCTGCAGCATTACCCACTTCACGGGAGAAGTGATGAGAACTGTTCTGGGGA
AGACGCTGCCCTCCTAGGGGAAAGGAACATCCCGTTTCAGGAGAGATATGACGTGCTTTCTCCAGAGGCTTCACAAAAGC
TGCTGTGATGGCTTCAGCCACGCCTGGTCCTGAATGACCACATGCACAGTGGCTGTGAGGTGCTGCATCTGGGAGGCATC
CCTGAACTCAGCATCCCGTCCTTTAGTTGGAGGGATAGAAACAACCCCAGTTTCATCATAGGCAGCATAACGTCCACAGG
ACATGCTCTCTCCAAGTGCTTCCTCCCT

Alignment

ORF - retro_ogar_2826 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 80.44 %
• Parental protein coverage: 56.42 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  KAWADDVERFQKMFRHPATKKKKVAGSNPQPGPFEFRMTTYKIKRFEKVFSSERLFSWKGINFVMINSVA
          KAWADDVERFQKMFRHP.....KV...N...G.F...MTTYKIK.FEK..SSERLFSWKGINFVMINS..
Retrocopy KAWADDVERFQKMFRHPGHVQLKVVAGNHDIG-FHYEMTTYKIKWFEKILSSERLFSWKGINFVMINSMV

Parental  LEGDRCTLCSKAEAELIAISHRLNCSREDPASHQCGEGQP-LPVSAPVLLQHYPLYRRSDENCSGEDAAP
          .EGDRC..CSKAEAELIAISHRLNCSRE.PASHQCGEGQP..PVSAPVLLQHYPL..RSDENCSGEDAA.
Retrocopy PEGDRCIPCSKAEAELIAISHRLNCSREEPASHQCGEGQP<IPVSAPVLLQHYPLHGRSDENCSGEDAAL

Parental  LEERNIPFQERYDVLSREASQKLLWWLRPRLVLSGHTHNSCEMLHPGGIPELSVPSFSWRNRNNPSFIMG
          L.ERNIPFQERYDVLS.EASQKLL.WL.PRLVL..H.H..CE.LH.GGIPELS.PSFSWR.RNNPSFI.G
Retrocopy LGERNIPFQERYDVLSPEASQKLL*WLQPRLVLNDHMHSGCEVLHLGGIPELSIPSFSWRDRNNPSFIIG

Parental  SITSTGHALSKCNLP
          SITSTGHALSKC.LP
Retrocopy SITSTGHALSKCFLP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Otolemur garnettii was not studied using RNA-Seq expression data.

ChIP-Seq

Otolemur garnettii was not studied using ChIP-Seq data.

EST

Otolemur garnettii was not studied using EST data.

TSS

Otolemur garnettii was not studied using FANTOM5 data.

Lab

retro_ogar_2826 was not experimentally validated.

Homology

Retrocopy orthology:

Otolemur garnettii does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 6 parental genes, and 7 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000154889	1 retrocopy	retro_hsap_1450,
Macaca mulatta	ENSMMUG00000011467	1 retrocopy	retro_mmul_2270,
Mus musculus	ENSMUSG00000062526	1 retrocopy	retro_mmus_869,
Otolemur garnettii	ENSOGAG00000007068	2 retrocopies	retro_ogar_1163, retro_ogar_2826 ,
Pongo abelii	ENSPPYG00000008997	1 retrocopy	retro_pabe_3557,
Pan troglodytes	ENSPTRG00000009872	1 retrocopy	retro_ptro_986,