RetrogeneDB ID: retro_mmus_718

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 11:66878455..66878673(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Hint1
• Ensembl ID: ENSMUSG00000020267
• Aliases: Hint1, AA673479, Hint, Ipk1, PKCI-1, PRKCNH1
• Description: histidine triad nucleotide binding protein 1 [Source:MGI Symbol;Acc:MGI:1321133]

Sequence

>retro_mmus_718
ATCTTCCACAAAGAAATCCTCATCAAGATCTTCAAGGACAGCCAGTGTCTTGCTTTTCATGACATTTCCCCTCAAGCACC
AAAACATTTCCTGGCGATACCCAAGAATATAGTCCAGATTTCTGTAGCGGAAGATGATAAAGTCTTCTAAGATGTCTAAT
AATTGTTGGCAAGAAATGTGCTGCAGATCTGGGCCTGAATTATGGTTGTCAGGTGGTT

Alignment

ORF - retro_mmus_718 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 67.53 %
• Parental protein coverage: 60.32 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  IIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDE-SLLGHLMIVGKKCAADLGL
          I..KEI..KI.F.D..CLAFHDISPQAP.HFL.IPK..I.QISVA..DD..SLL..L.IVGKKCAADLGL
Retrocopy IFHKEILIKI-FKDSQCLAFHDISPQAPKHFLAIPK-NIVQISVAE-DDK<SLLRCLIIVGKKCAADLGL

Parental  KRGYRMV
          ..G...V
Retrocopy NYGCQVV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	76.09 RPM
SRP007412_cerebellum	0.00 RPM	88.71 RPM
SRP007412_heart	0.00 RPM	98.90 RPM
SRP007412_kidney	0.00 RPM	170.96 RPM
SRP007412_liver	0.00 RPM	161.99 RPM
SRP007412_testis	0.00 RPM	97.42 RPM

ChIP-Seq

RNA Polymerase II actvity near the 5' end of retro_mmus_718 was not detected

EST

No EST(s) were mapped for retro_mmus_718 retrocopy.

TSS

No TSS is located nearby retro_mmus_718 retrocopy 5' end.

Lab

retro_mmus_718 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_718 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 22 parental genes, and 44 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000032152	1 retrocopy	retro_cfam_473,
Callithrix jacchus	ENSCJAG00000014398	3 retrocopies	retro_cjac_134, retro_cjac_142, retro_cjac_87,
Equus caballus	ENSECAG00000023180	3 retrocopies	retro_ecab_264, retro_ecab_356, retro_ecab_550,
Erinaceus europaeus	ENSEEUG00000008175	1 retrocopy	retro_eeur_582,
Echinops telfairi	ENSETEG00000010127	1 retrocopy	retro_etel_1,
Homo sapiens	ENSG00000169567	1 retrocopy	retro_hsap_3913,
Gorilla gorilla	ENSGGOG00000011967	1 retrocopy	retro_ggor_89,
Macropus eugenii	ENSMEUG00000005368	2 retrocopies	retro_meug_1001, retro_meug_848,
Myotis lucifugus	ENSMLUG00000001091	2 retrocopies	retro_mluc_1388, retro_mluc_2100,
Macaca mulatta	ENSMMUG00000009985	2 retrocopies	retro_mmul_1896, retro_mmul_759,
Monodelphis domestica	ENSMODG00000028727	3 retrocopies	retro_mdom_102, retro_mdom_1741, retro_mdom_286,
Mustela putorius furo	ENSMPUG00000011639	4 retrocopies	retro_mputfur_1337, retro_mputfur_1376, retro_mputfur_45, retro_mputfur_93,
Mus musculus	ENSMUSG00000020267	1 retrocopy	retro_mmus_718 ,
Nomascus leucogenys	ENSNLEG00000012431	1 retrocopy	retro_nleu_2155,
Oryctolagus cuniculus	ENSOCUG00000006607	5 retrocopies	retro_ocun_1374, retro_ocun_214, retro_ocun_643, retro_ocun_821, retro_ocun_968,
Otolemur garnettii	ENSOGAG00000008850	2 retrocopies	retro_ogar_1028, retro_ogar_1599,
Procavia capensis	ENSPCAG00000004737	1 retrocopy	retro_pcap_407,
Pongo abelii	ENSPPYG00000015747	2 retrocopies	retro_pabe_3189, retro_pabe_909,
Pan troglodytes	ENSPTRG00000017206	1 retrocopy	retro_ptro_2661,
Rattus norvegicus	ENSRNOG00000000622	1 retrocopy	retro_rnor_98,
Sarcophilus harrisii	ENSSHAG00000005834	2 retrocopies	retro_shar_113, retro_shar_301,
Ictidomys tridecemlineatus	ENSSTOG00000027920	4 retrocopies	retro_itri_1129, retro_itri_114, retro_itri_177, retro_itri_260,