RetrogeneDB ID: retro_mmus_2381

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 4:100581283..100581607(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMUSG00000082601
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Ncbp2
• Ensembl ID: ENSMUSG00000022774
• Aliases: Ncbp2, 20kDa, 5930413E18Rik, AA536802, AI843301, C79367
• Description: nuclear cap binding protein subunit 2 [Source:MGI Symbol;Acc:MGI:1915342]

Sequence

>retro_mmus_2381
GGCTTACTGAAGGCGCTGCACAGCGATTCCTACGTGGAACTCAGCAAATACCAGGACTAGCACTTCCTGGGCGACAATGA
AGAACAAGAAAAGTTACTGAAGGAAAGCTGTACATTGTATGTTGGAAATCTTTCCTTTTATATAACTGAAGAACAGATTT
ACAAACTCTTCAGCAAAAGTGGTCATATAAAGAAGATCATCATGGATCTGGATAAAATGAAGAAAACAGCATGTGGATTC
TGTTTTGTGAAATACTATTCAAGAGCCGATGCAGAGAACACAATGTGGTCCATAAACGGAACTCATCTGGATGACCGGAT
CATA

Alignment

ORF - retro_mmus_2381 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 86.11 %
• Parental protein coverage: 69.23 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  GLLKALRSDSYVELSEYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGL
          GLLKAL.SDSYVELS.Y.D.HF.GDNEEQEKLLK.SCTLYVGNLSFY.TEEQIY.LFSKSG.IKKIIM.L
Retrocopy GLLKALHSDSYVELSKYQD*HFLGDNEEQEKLLKESCTLYVGNLSFYITEEQIYKLFSKSGHIKKIIMDL

Parental  DKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRII
          DKMKKTACGFCFV.YYSRADAEN.M..INGT.LDDRII
Retrocopy DKMKKTACGFCFVKYYSRADAENTMWSINGTHLDDRII

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	39.79 RPM
SRP007412_cerebellum	0.00 RPM	34.35 RPM
SRP007412_heart	0.00 RPM	22.76 RPM
SRP007412_kidney	0.00 RPM	31.94 RPM
SRP007412_liver	0.00 RPM	18.35 RPM
SRP007412_testis	0.00 RPM	34.30 RPM

ChIP-Seq

RNA Polymerase II actvity near the 5' end of retro_mmus_2381 was not detected

EST

No EST(s) were mapped for retro_mmus_2381 retrocopy.

TSS

No TSS is located nearby retro_mmus_2381 retrocopy 5' end.

Lab

retro_mmus_2381 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_2381 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 25 parental genes, and 43 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000003664	2 retrocopies	retro_amel_113, retro_amel_62,
Bos taurus	ENSBTAG00000008873	1 retrocopy	retro_btau_1819,
Canis familiaris	ENSCAFG00000013100	2 retrocopies	retro_cfam_152, retro_cfam_2195,
Callithrix jacchus	ENSCJAG00000013735	2 retrocopies	retro_cjac_3139, retro_cjac_4103,
Cavia porcellus	ENSCPOG00000002976	1 retrocopy	retro_cpor_611,
Equus caballus	ENSECAG00000016153	1 retrocopy	retro_ecab_79,
Felis catus	ENSFCAG00000029865	2 retrocopies	retro_fcat_1936, retro_fcat_561,
Homo sapiens	ENSG00000114503	1 retrocopy	retro_hsap_5,
Loxodonta africana	ENSLAFG00000006372	1 retrocopy	retro_lafr_129,
Macropus eugenii	ENSMEUG00000004730	1 retrocopy	retro_meug_34,
Microcebus murinus	ENSMICG00000003162	1 retrocopy	retro_mmur_488,
Myotis lucifugus	ENSMLUG00000017500	2 retrocopies	retro_mluc_355, retro_mluc_592,
Mustela putorius furo	ENSMPUG00000003806	1 retrocopy	retro_mputfur_9,
Mus musculus	ENSMUSG00000022774	2 retrocopies	retro_mmus_2381 , retro_mmus_2645,
Nomascus leucogenys	ENSNLEG00000001727	1 retrocopy	retro_nleu_1239,
Oryctolagus cuniculus	ENSOCUG00000006738	2 retrocopies	retro_ocun_1887, retro_ocun_833,
Otolemur garnettii	ENSOGAG00000005009	6 retrocopies	retro_ogar_3151, retro_ogar_3152, retro_ogar_3153, retro_ogar_3160, retro_ogar_3161, retro_ogar_3162,
Pongo abelii	ENSPPYG00000014449	1 retrocopy	retro_pabe_85,
Pan troglodytes	ENSPTRG00000015789	1 retrocopy	retro_ptro_3151,
Pteropus vampyrus	ENSPVAG00000017273	3 retrocopies	retro_pvam_238, retro_pvam_305, retro_pvam_939,
Sarcophilus harrisii	ENSSHAG00000004363	2 retrocopies	retro_shar_161, retro_shar_46,
Tupaia belangeri	ENSTBEG00000015222	3 retrocopies	retro_tbel_2153, retro_tbel_3367, retro_tbel_758,
Tarsius syrichta	ENSTSYG00000014263	1 retrocopy	retro_tsyr_2008,
Tursiops truncatus	ENSTTRG00000013908	2 retrocopies	retro_ttru_442, retro_ttru_826,
Vicugna pacos	ENSVPAG00000010369	1 retrocopy	retro_vpac_493,