RetrogeneDB ID: retro_mmul_2629

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: X:117126831..117127332(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: AKR7A2
• Ensembl ID: ENSMMUG00000006891
• Aliases: None
• Description: aflatoxin B1 aldehyde reductase member 2 [Source:RefSeq peptide;Acc:NP_001252627]

Sequence

>retro_mmul_2629
GGCTGGATCCTGCCCACTGTGTACCAGGGCATGTACAATGCCACCACCTGGCAGGTGGAAATGGAGCTCTTCCCCTGCCT
CGGGCACTTTGGACTGAGGTTCTATGCCTACACCCTCTGGCTGGGGGCCTGCTGACCGGCAAGTACGAGGCCAGGGCAAG
AAACAGCCCGGGGGCCACTTCTTTGGGAATAGCTGGGCTGAGACCTACAGGAATCGCTTCTGGAAGGAGCACCACTTCAA
GGCCATTGCCCTGGTGGAGAAGGCCATGCAGGCTGTGTATGGTGCCAGTGCCCCAGTATGACCTCGGCCACCCTCTGGTG
GATGTACCACCACTTACAGCTGCAGGGTGCCCATGGAGACGCGGTCATCCTGGGCATGTCCAGCCTGGAGAAGCTGGAGC
AGAACTTGGCAGCGATGGAGAAAGGGCCCATGGAACCGACTGCCATGGACACTTTTAATCAAACCTGGCATTTGGTTGCC
CACGAATGTCCCAACTACTTC

Alignment

ORF - retro_mmul_2629 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.77 %
• Parental protein coverage: 51.52 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  GWIVPTVYQGMYNATTRQVETELLPCLRHFGLRFYAY-NPLAGGLLTGKYKYEDK-DGKQPVGRFFGNSW
          GWI.PTVYQGMYNATT.QVE.EL.PCL.HFGLRFYAY..PLAGGLLTG..KYE.....KQP.G.FFGNSW
Retrocopy GWILPTVYQGMYNATTWQVEMELFPCLGHFGLRFYAY<HPLAGGLLTG--KYEAR<GKKQPGGHFFGNSW

Parental  AETYRNRFWKEHHFQAIALVEKALQAAYGTSVP-SMTSAALRWMYHHSQLQGAHGDTVILGMSSLEQLEQ
          AETYRNRFWKEHHF.AIALVEKA.QA.YG.S.P.SMTSA.L.WMYHH.QLQGAHGD.VILGMSSLE.LEQ
Retrocopy AETYRNRFWKEHHFKAIALVEKAMQAVYGASAP<SMTSATLWWMYHHLQLQGAHGDAVILGMSSLEKLEQ

Parental  NLAATEEGPLEPAVVDAFNQAWHLVAHECPNYF
          NLAA.E.GP.EP...D.FNQ.WHLVAHECPNYF
Retrocopy NLAAMEKGPMEPTAMDTFNQTWHLVAHECPNYF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.22 RPM	7.17 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	27.29 RPM
SRP007412_cerebellum	0.00 RPM	8.78 RPM
SRP007412_heart	0.00 RPM	11.19 RPM
SRP007412_kidney	0.12 RPM	398.11 RPM
SRP007412_liver	0.00 RPM	715.60 RPM
SRP007412_testis	0.00 RPM	9.61 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_2629 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_2629 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_2629 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 5 parental genes, and 5 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000162482	1 retrocopy	retro_hsap_208,
Macaca mulatta	ENSMMUG00000006891	1 retrocopy	retro_mmul_2629 ,
Nomascus leucogenys	ENSNLEG00000007852	1 retrocopy	retro_nleu_1857,
Pongo abelii	ENSPPYG00000001793	1 retrocopy	retro_pabe_431,
Pan troglodytes	ENSPTRG00000000265	1 retrocopy	retro_ptro_336,