RetrogeneDB ID: retro_mdom_989

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 3:133169718..133170348(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RAB2A
• Ensembl ID: ENSMODG00000008556
• Aliases: None
• Description: RAB2A, member RAS oncogene family [Source:HGNC Symbol;Acc:9763]

Sequence

>retro_mdom_989
TTGGCGTATGCTTATCTCTTCAAGTACATCATCTTCTGCATCAAAGGTGTTGGGAAATCATGTATATTGCTACAGTTTAC
AGAGAAGAGGTTTCAGCCAGTACCTGACCTTACTATTGGTGTAGAATTTGGTGCTCCAACGATAACTATTGGTGGAAAAC
AGAGAAAACTTCAGATATGGGATACAGAGGGGTAAGAATCCTTCCATTCCATCACAAGGTCATATTACAGAGGTGCAACA
GGAGCTTTACTAGTATATGATATTATAAGGAGTGATACATTCAACAATTTGACAACTTGGTTAGAAGCTGCTTGCCAGCA
TTCCAATTCCAACAGAGTCATTATGCTTATAATGTGGAATAAAAGTGATTTAGAAGCTAGAAGAGAAGTAAAAAGAGGTG
AAATTTTTGCCTGAGAACATGGACTTATCTTTATGGAAACTTCTGCTAAGACTGCTTTCAATGTAGAAGAGGAATTTATT
AATACAGGGAGATAAATTTATGAAAAAATCCAAGGAGTTTTTGACGTTAATAATGAGGCAAATGGCATTAAAACCGGTCC
TCAGAATGATGCTACTAATGCAACACATACTGGCAGTCAGGGAGGAAAACAAGCTGGTGGAGGCTGCTGT

Alignment

ORF - retro_mdom_989 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 80.28 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 3
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRS
          .AYAYLFKYII....GVGKSC.LLQFT.KRFQPV.DLTIGVEFGA..ITI.GKQ.KLQIWDT.G.ESF.S
Retrocopy LAYAYLFKYIIFCIKGVGKSCILLQFTEKRFQPVPDLTIGVEFGAPTITIGGKQRKLQIWDTEG*ESFHS

Parental  ITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLI-GNKSDLESRREVKKEEGEAFAR
          ITRSYYRGA.GALLVYDI.R.DTFN.LTTWLE.A.QHSNSN.VIMLI..NKSDLE.RREVK...GE.FA.
Retrocopy ITRSYYRGATGALLVYDIIRSDTFNNLTTWLEAACQHSNSNRVIMLIMWNKSDLEARREVKR--GEIFA*

Parental  EHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGSQGGQQAGG
          EHGLIFMETSAKTA.NVEE.FINT...IYEKIQ.GVFD.NNEANGIK.GPQ..ATNATH.GSQGG.QAGG
Retrocopy EHGLIFMETSAKTAFNVEEEFINTGR*IYEKIQ-GVFDVNNEANGIKTGPQNDATNATHTGSQGGKQAGG

Parental  GCC
          GCC
Retrocopy GCC

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	0.00 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_989 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_989 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 10 parental genes, and 13 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000007153	1 retrocopy	retro_cfam_2057,
Equus caballus	ENSECAG00000012124	1 retrocopy	retro_ecab_970,
Erinaceus europaeus	ENSEEUG00000007700	1 retrocopy	retro_eeur_496,
Echinops telfairi	ENSETEG00000010340	2 retrocopies	retro_etel_203, retro_etel_32,
Monodelphis domestica	ENSMODG00000008556	2 retrocopies	retro_mdom_1999, retro_mdom_989 ,
Monodelphis domestica	ENSMODG00000016955	1 retrocopy	retro_mdom_1710,
Mus musculus	ENSMUSG00000047187	1 retrocopy	retro_mmus_2650,
Sorex araneus	ENSSARG00000013511	2 retrocopies	retro_sara_688, retro_sara_744,
Tarsius syrichta	ENSTSYG00000013060	1 retrocopy	retro_tsyr_1215,
Tursiops truncatus	ENSTTRG00000009615	1 retrocopy	retro_ttru_1377,