RetrogeneDB ID: retro_ggor_565

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 10:11082254..11082603(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ORMDL1
• Ensembl ID: ENSGGOG00000015259
• Aliases: None
• Description: None

Sequence

>retro_ggor_565
GTCTTACTTAGCATTCCTTCTTCCGTGTTCTCATTGCTTAGACCTTAACAAATATTATACATAATCTGGGGATGAATGGA
TTTTTCCATGCTTGAAAGGAACACCTTTGGAAACCCCTGACCAGGGTAAAGCAAGGCTCCCAACGCACTGCGAACAACTG
GGTGACGGAGTACCGTTTACATCTTCACGGAAGTTTTTCACCGTTTCTCCAATCATTCTATGTTTTCCAGCAAGTTTCTA
TAGAAGTATGCTCCAACTCACTCCATCGTAAGCACGGCTTCTCTCCTGAGTACGCTAAACTCCCCAAATGCAGCAACAAC
ACAGTGTTCCGATCTTTGGAATTAATAAG

Alignment

ORF - retro_ggor_565 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 72.73 %
• Parental protein coverage: 76.47 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  VLLSIP-FFSVPVAWTLTNIIHNLGMYVFLHA-VKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFT
          VLLSIP.FF.V..A.TLTNIIHNLGM..F.HA..KGTP.ETPDQGKARL.TH.EQL..GV.FTSSRKFFT
Retrocopy VLLSIP<FFRVLIA*TLTNIIHNLGMNGFFHA<LKGTPLETPDQGKARLPTHCEQLGDGVPFTSSRKFFT

Parental  ISPIILYFLASFYT-KYDPTHFILNTASLLSVL-IPKMPQLHGVRIFGINK
          .SPIIL.F.ASFY..KY.PTH.I..TASLLS.L..P.M.Q.H.V.IFGINK
Retrocopy VSPIILCFPASFYR<KYAPTHSIVSTASLLSTL>TPQMQQQHSVPIFGINK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	23.45 RPM
SRP007412_cerebellum	0.00 RPM	24.70 RPM
SRP007412_heart	0.00 RPM	3.85 RPM
SRP007412_kidney	0.04 RPM	31.85 RPM
SRP007412_liver	0.00 RPM	27.12 RPM
SRP007412_testis	0.21 RPM	39.26 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_565 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_565 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_645
Pan troglodytes	retro_ptro_469
Macaca mulatta	retro_mmul_2432

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Parental genes homology:

Parental genes homology involve 12 parental genes, and 14 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000005579	1 retrocopy	retro_cjac_2962,
Homo sapiens	ENSG00000128699	1 retrocopy	retro_hsap_645,
Gorilla gorilla	ENSGGOG00000015259	1 retrocopy	retro_ggor_565 ,
Loxodonta africana	ENSLAFG00000007769	1 retrocopy	retro_lafr_411,
Myotis lucifugus	ENSMLUG00000014339	1 retrocopy	retro_mluc_2318,
Macaca mulatta	ENSMMUG00000014316	1 retrocopy	retro_mmul_2432,
Nomascus leucogenys	ENSNLEG00000006625	1 retrocopy	retro_nleu_730,
Pongo abelii	ENSPPYG00000013017	2 retrocopies	retro_pabe_570, retro_pabe_571,
Pan troglodytes	ENSPTRG00000012736	1 retrocopy	retro_ptro_469,
Sus scrofa	ENSSSCG00000016044	1 retrocopy	retro_sscr_247,
Tupaia belangeri	ENSTBEG00000012942	1 retrocopy	retro_tbel_10,
Tursiops truncatus	ENSTTRG00000005240	2 retrocopies	retro_ttru_1846, retro_ttru_770,