RetrogeneDB ID: retro_ggor_313

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:150601076..150601516(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: GM2A
• Ensembl ID: ENSGGOG00000015302
• Aliases: None
• Description: None

Sequence

>retro_ggor_313
GTGCAATCCCTGATGGAGGCTCCACTCCTGATTGTCCTGGGCTTGCTTCTTGCAGGCCTAGCAGCCCCTGCCCACGTCCA
CCTGAACCAGATTAGTAGCTTTCCCTGGGATAACTGGGACAAAGGGAAGGACCCTGTGGTGATCAAAAGCCTGTCTCTGG
AAGCTGACCCCAACGTAGTTCCTGGGAACGTGATCGTCAGTGCTGAGGACAAGAACCAGTGTCCCCCTCAAATCTCCTCT
GAAGGGAGGAATTAACTGTAGAGAAGGAAGTGTCTGGCTTCTGGGTCAAGATCTCATGCATGGAACAGATTGGCGGCTGT
GCCTATGAAAACTTCTGTGATGTGTTTGATATTTTCATTCCCCCTGGGGAGCCCTGCCCAGAGCCCCTGCATACCTATGG
GCTTCTTTGCCACTGTCCCTTCAAAGTAGGCACCTACTCA

Alignment

ORF - retro_ggor_313 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 64.24 %
• Parental protein coverage: 75.65 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MQSLMQSPLLIALGLL---LAAPAQAHLKKPSQLSSFSWDNCDEGKDPAVIRSLTLEPDPIIVPGNVTLS
          .QSLM..PLLI.LGLL...LAAPA..HL....Q.SSF.WDN.D.GKDP.VI.SL.LE.DP..VPGNV..S
Retrocopy VQSLMEAPLLIVLGLLLAGLAAPAHVHL---NQISSFPWDNWDKGKDPVVIKSLSLEADPNVVPGNVIVS

Parental  VVGS-TSVPLSSPLK-VDLVLEKEVAGLWIKIPCTDYIGSCTFEHFCDVLDMLIPTGEPCPEPLRTYGLP
          .....TSVPL.SPLK...L..EKEV.G.W.KI.C...IG.C..E.FCDV.D..IP.GEPCPEPL.TYGL.
Retrocopy AEDK>TSVPLKSPLK>EELTVEKEVSGFWVKISCMEQIGGCAYENFCDVFDIFIPPGEPCPEPLHTYGLL

Parental  CHCPFKEGTYS
          CHCPFK.GTYS
Retrocopy CHCPFKVGTYS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	25.61 RPM
SRP007412_cerebellum	0.00 RPM	27.18 RPM
SRP007412_heart	0.00 RPM	16.14 RPM
SRP007412_kidney	0.12 RPM	27.23 RPM
SRP007412_liver	0.00 RPM	32.13 RPM
SRP007412_testis	0.00 RPM	28.18 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_313 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_313 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_264
Macaca mulatta	retro_mmul_454

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 17 retrocopies.

Species	Parental gene accession	Retrocopies number
Equus caballus	ENSECAG00000020587	1 retrocopy	retro_ecab_510,
Homo sapiens	ENSG00000196743	2 retrocopies	retro_hsap_264, retro_hsap_2715,
Gorilla gorilla	ENSGGOG00000015302	2 retrocopies	retro_ggor_1891, retro_ggor_313 ,
Macropus eugenii	ENSMEUG00000010421	1 retrocopy	retro_meug_1818,
Microcebus murinus	ENSMICG00000000690	1 retrocopy	retro_mmur_518,
Myotis lucifugus	ENSMLUG00000003215	1 retrocopy	retro_mluc_920,
Macaca mulatta	ENSMMUG00000022869	1 retrocopy	retro_mmul_454,
Nomascus leucogenys	ENSNLEG00000010966	1 retrocopy	retro_nleu_866,
Oryctolagus cuniculus	ENSOCUG00000015837	1 retrocopy	retro_ocun_704,
Ochotona princeps	ENSOPRG00000006171	1 retrocopy	retro_opri_1169,
Pongo abelii	ENSPPYG00000015962	1 retrocopy	retro_pabe_403,
Pan troglodytes	ENSPTRG00000017431	2 retrocopies	retro_ptro_1834, retro_ptro_221,
Ictidomys tridecemlineatus	ENSSTOG00000028500	1 retrocopy	retro_itri_759,
Tursiops truncatus	ENSTTRG00000000503	1 retrocopy	retro_ttru_488,