RetrogeneDB ID: retro_ggor_1554

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 21:1996445..1996953(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000023667
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: FAM207A
• Ensembl ID: ENSGGOG00000014482
• Aliases: None
• Description: None

Sequence

>retro_ggor_1554
TTCATCAACACCAACATCTTTGCCAGGACCAAGATAGACCCCAGCGCCTTGGTGCAGACGCTGGAGCTGGATGTCAGGAG
CGTAACTTCCATCAGGAGAGGGGCAGAGGCCAAGACCGTTTTGCCCAAGAAGGAGAAAATGAAGCTGAGGCGTGAGCAAT
GCTTGCAGAAAATCGAAGCCATAAAACTGGCTGAGCAGAAGCACAGGGAGGAGCGGAGGCGGAGGGCCACGGTGGTGGTG
GGGGACCTGCACCCGCTCAGGGATGCCCTGCCCGAGCTGCTGGGGCTCGAGGCTGGCAGCCGGCGCCAAGCCTGCAGCAG
GGAGAGCAACAAGCCCCGGGCCGTCAGAGCTCAGCCGGATGAGCGCAGCCCAGAGACAGCACCTTCTCGAGGAAGGAAGG
ACCCGGTTTCAGGAGCTGCTGGGCAGTCCGGCCTACAGAGCCAGCCCCCTGGTGGCCATCGGGCAGACGCTGGCCCGGCA
GATGCAGCTGGAAGACGGCGGCCAGCTC

Alignment

ORF - retro_ggor_1554 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 95.29 %
• Parental protein coverage: 77.52 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  FINTNIFARTKIDPSALVQKLELDVRSVTSVRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHRE
          FINTNIFARTKIDPSALVQ.LELDVRSVTS.RRGAEAKTVLPKKEKMKLRREQ.LQKIEAIKLAEQKHRE
Retrocopy FINTNIFARTKIDPSALVQTLELDVRSVTSIRRGAEAKTVLPKKEKMKLRREQCLQKIEAIKLAEQKHRE

Parental  ERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPR-PSELSRMSAAQRQQLLEEERTRFQEL
          ERRRRATVVVGDLHPLRDALPELLGLEAGSRRQA.SRESNKPR.PSELSRMSAAQRQ.LLEE.RTRFQEL
Retrocopy ERRRRATVVVGDLHPLRDALPELLGLEAGSRRQACSRESNKPR>PSELSRMSAAQRQHLLEEGRTRFQEL

Parental  LASPAYRASPLVAIGQTLARQMQLEDGGQL
          L.SPAYRASPLVAIGQTLARQMQLEDGGQL
Retrocopy LGSPAYRASPLVAIGQTLARQMQLEDGGQL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	4.36 RPM
SRP007412_cerebellum	0.04 RPM	4.85 RPM
SRP007412_heart	0.03 RPM	5.35 RPM
SRP007412_kidney	0.00 RPM	3.11 RPM
SRP007412_liver	0.03 RPM	3.64 RPM
SRP007412_testis	0.10 RPM	6.01 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1554 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1554 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 9 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000160256	4 retrocopies	retro_hsap_1167, retro_hsap_1916, retro_hsap_2494, retro_hsap_4325,
Gorilla gorilla	ENSGGOG00000014482	1 retrocopy	retro_ggor_1554 ,
Loxodonta africana	ENSLAFG00000010542	1 retrocopy	retro_lafr_919,
Pan troglodytes	ENSPTRG00000013995	3 retrocopies	retro_ptro_1246, retro_ptro_1446, retro_ptro_803,