RetrogeneDB ID: retro_ggor_1531

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 20:21430976..21431494(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MRPS11
• Ensembl ID: ENSGGOG00000015152
• Aliases: None
• Description: None

Sequence

>retro_ggor_1531
AGGGTCATGGCCAGGATGCTGGTGCAGACCATCCACACAGGCACCCAGAAGCTCCAAGACATTGAGGCCAAGCAGAACAT
TGAAGAGAAGATGGTAGCTCCCAGCTACACCAGCTTTAGCATTTACCCTCCCATTACAAAAGAAAAAAGCTCTCTGAGGT
GGGCAGGAAAGAAATTTGAGGAGATCCCAATTGCACACATTAGAGCATCCTACAACAACACACAGATCCAGGTAATCTCT
GCCACTAATCAGCCCCTTGCCCATACTTCCTGTGGGACAGAGGAATTTCTGAATGCCAAGAAGGGCACAGGCATTGATGC
ACAGACAGCAGGCATAGCAGCCATGACAAAAGCTGCAGGAAAGGGTGTTACCCACACCTGAGTTGTGGTGAAAGGCCAGG
GGCCAGGACACCTGTCTGCCATCCAGGGACTGACCATGGGGGGCCTGGAAGTGATCTCAATCACAACAACACCCCCATCC
CACACAATGGCTCCTGCCCCCAGAAGGCTCCGAGGCTG

Alignment

ORF - retro_ggor_1531 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 70.11 %
• Parental protein coverage: 88.66 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  RVVARTPAGTICTGARQLQDAAAKQKVEQN-AAPSHTKFSIYPPIPGEESSLRWAGKKFEEIPIAHIKAS
          RV.AR....TI.TG...LQD..AKQ..E....APS.T.FSIYPPI..E.SSLRWAGKKFEEIPIAHI.AS
Retrocopy RVMARMLVQTIHTGTQKLQDIEAKQNIEEKMVAPSYTSFSIYPPITKEKSSLRWAGKKFEEIPIAHIRAS

Parental  HNNTQIQVVSASNEPLAFASCGTEGFRNAKKGTGIAAQTAGIAAAARAKQKGVIHIRVVVKGLGPGRLSA
          .NNTQIQV.SA.N.PLA..SCGTE.F.NAKKGTGI.AQTAGIAA...A..KGV.H..VVVKG.GPG.LSA
Retrocopy YNNTQIQVISATNQPLAHTSCGTEEFLNAKKGTGIDAQTAGIAAMTKAAGKGVTHT*VVVKGQGPGHLSA

Parental  MHGLIMGGLEVISIT-DNTPIPHNGCRPRKARKL
          ..GL.MGGLEVISIT..NTPIPHNG..P.KA..L
Retrocopy IQGLTMGGLEVISIT<NNTPIPHNGSCPQKAPRL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	23.55 RPM
SRP007412_cerebellum	0.00 RPM	16.86 RPM
SRP007412_heart	0.00 RPM	14.60 RPM
SRP007412_kidney	0.00 RPM	21.79 RPM
SRP007412_liver	0.00 RPM	12.95 RPM
SRP007412_testis	0.00 RPM	25.17 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1531 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1531 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2458
Pan troglodytes	retro_ptro_1419
Macaca mulatta	retro_mmul_637

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Parental genes homology:

Parental genes homology involve 9 parental genes, and 11 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000013012	2 retrocopies	retro_cjac_2601, retro_cjac_2989,
Felis catus	ENSFCAG00000014967	1 retrocopy	retro_fcat_282,
Homo sapiens	ENSG00000181991	1 retrocopy	retro_hsap_2458,
Gorilla gorilla	ENSGGOG00000015152	1 retrocopy	retro_ggor_1531 ,
Macaca mulatta	ENSMMUG00000013659	1 retrocopy	retro_mmul_637,
Nomascus leucogenys	ENSNLEG00000011441	1 retrocopy	retro_nleu_1902,
Ochotona princeps	ENSOPRG00000008247	1 retrocopy	retro_opri_540,
Pongo abelii	ENSPPYG00000006751	2 retrocopies	retro_pabe_1808, retro_pabe_2583,
Pan troglodytes	ENSPTRG00000007420	1 retrocopy	retro_ptro_1419,