RetrogeneDB ID: retro_ggor_1255

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 16:11769576..11769925(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MRPL18
• Ensembl ID: ENSGGOG00000014075
• Aliases: None
• Description: None

Sequence

>retro_ggor_1255
GCTGCAGAGAAACAAGGTAGTGCCACACACCTGAGCTCCAGTGAGTTCCGGCATGGGTGGTGAGTTCCAAGGACTCAGCA
GCATAAAGCATTGGTTGAACATCCAAATGGCCAGGTTGTGATTTCAGCGTCCAGTTATGAGTGCACTATAAAAAGCACCG
TTCTAGTACCAAAAATGTGACTGGTGAGAATATACGACAACTGCTTGCAGAGCCAGGCTTAAGGCAGGAATCAACTTCAT
GGTCTACCAACCAGACCCTTGGGAGGCAGCCTTGGACTCGATGAGACAACTATGAAGTGCCAAGACAGGAGGTGCTGTGG
CTCCACGGGAACCTCGGAGAATCTGTGAA

Alignment

ORF - retro_ggor_1255 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 55.37 %
• Parental protein coverage: 66.11 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  ARKERGWRTVFPSREFWHRLRVIRTQHHVEALVEHQSGKVVVSASTREWAIK-KHLYSTRNVVACESIGR
          A....G..T...S.EF.H...V.RTQ.H..ALVEH..G.VV.SAS..E..IK.KH..ST.NV...E.I..
Retrocopy AAEKQGSATHLSSSEFRHGW*VPRTQQH-KALVEHPNGQVVISASSYECTIK<KHRSSTKNVTG-ENIRQ

Parental  VLAQ-RCLEAGINFMVYQPTPWEAASDSMKRLQSAMTEGGVVLREPQRIYE
          .LA....L.AGINFMVYQP.PWEAA.DSM..L.SA.T.G.V..REP.RI.E
Retrocopy LLAE<ARLKAGINFMVYQPDPWEAALDSMRQL*SAKTGGAVAPREPRRICE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	22.15 RPM
SRP007412_cerebellum	0.04 RPM	15.33 RPM
SRP007412_heart	0.00 RPM	9.76 RPM
SRP007412_kidney	0.00 RPM	24.62 RPM
SRP007412_liver	0.03 RPM	20.05 RPM
SRP007412_testis	0.41 RPM	38.75 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1255 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1255 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1664
Pan troglodytes	retro_ptro_1128

---

Parental genes homology:

Parental genes homology involve 12 parental genes, and 15 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000015398	1 retrocopy	retro_amel_1445,
Dipodomys ordii	ENSDORG00000011514	1 retrocopy	retro_dord_741,
Echinops telfairi	ENSETEG00000007591	1 retrocopy	retro_etel_438,
Homo sapiens	ENSG00000112110	1 retrocopy	retro_hsap_1664,
Gorilla gorilla	ENSGGOG00000014075	1 retrocopy	retro_ggor_1255 ,
Macaca mulatta	ENSMMUG00000017037	1 retrocopy	retro_mmul_61,
Mus musculus	ENSMUSG00000057388	1 retrocopy	retro_mmus_1940,
Otolemur garnettii	ENSOGAG00000007327	1 retrocopy	retro_ogar_1660,
Pongo abelii	ENSPPYG00000017147	3 retrocopies	retro_pabe_1416, retro_pabe_1418, retro_pabe_1421,
Pan troglodytes	ENSPTRG00000018761	1 retrocopy	retro_ptro_1128,
Pteropus vampyrus	ENSPVAG00000005322	2 retrocopies	retro_pvam_1480, retro_pvam_252,
Tarsius syrichta	ENSTSYG00000005598	1 retrocopy	retro_tsyr_1847,