RetrogeneDB ID: retro_ggor_1020

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 14:2094300..2094962(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SMARCE1
• Ensembl ID: ENSGGOG00000011803
• Aliases: None
• Description: None

Sequence

>retro_ggor_1020
AAGCATACAGCCACTGCCTGTTTCCAGAGAAACCACAGCCTCATCAATGAAATCCTTAGTGACAGTGTGGTGCCAGACAT
TCAGTCAGTTGTCACAACGGCTAGAATGCAGGTCCTCAAATGACAGGTCCAGTCCTTAATGGTTCATCAGCAAAAACTAG
AAGCTGAACTTCTTCAAGCAGAGGAACGATACCAGAAGACGAGGAAATTCCTGGAAAGCACAGATTCATTTAGCAATAAC
TTAAAAGGTTGTGCGGTCTGAAGGTAGAAGTGGATACGGAGAAAATTGCAGCTGAGATTGCACAGGCAGAGGAACAGGCC
CACAAAAGGCAGGAGGAAAGGGAGAGGGAGGTGGCAGACCAAGCTAAGCACAGTCAGAGCGGCATCGTTCCTGAGCAAGA
GCACGCGGCCAACTAAGGTGAGGAGAAGAAAGACGACGAGAACATTCCAATGGAGACAGGGGAGACACACCTTGAAGAAA
TGACAGAGAGCCAACAGAACAGTGAAGAAGGCACATCTACTCCTTAAGACAAGGAGAGTGGGCAGGAGGGGATCGACAGT
ATGGCAGAGGAAGGAACCAGTGATAGTAACACTGACTCGGAGAGCGACAGCCCAACAGTGGAGGAGTCACCAACAGATCC
CATACCAGAAGATGAGAAAAAA

Alignment

ORF - retro_ggor_1020 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.86 %
• Parental protein coverage: 54.01 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  KHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRK
          KHTATA.FQRNH.LI.EILS.SVVPD..SVVTTARMQVLK.QVQSLMVHQ.KLEAELLQ.EER.Q.K.RK
Retrocopy KHTATACFQRNHSLINEILSDSVVPDIQSVVTTARMQVLK*QVQSLMVHQQKLEAELLQAEERYQ-KTRK

Parental  FLESTDSFNNELK-RLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIIPEEEQAAN
          FLESTDSF.N.LK.RLCGLKVEVD.EKIAAEIAQAEEQA.KRQEERE.E.A.QA..SQS.I.PE.E.AAN
Retrocopy FLESTDSFSNNLK<RLCGLKVEVDTEKIAAEIAQAEEQAHKRQEEREREVADQAKHSQSGIVPEQEHAAN

Parental  KGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVE
          .GEEKKDDENIPMET.ETHLEE.TESQQN.EEGTSTP.DKESGQEG.DSMAEEGTSDSNT.SES.S.TVE
Retrocopy *GEEKKDDENIPMETGETHLEEMTESQQNSEEGTSTP*DKESGQEGIDSMAEEGTSDSNTDSESDSPTVE

Parental  EPPTDPIPEDEKK
          E.PTDPIPEDEKK
Retrocopy ESPTDPIPEDEKK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.24 RPM	38.36 RPM
SRP007412_cerebellum	0.28 RPM	34.63 RPM
SRP007412_heart	0.00 RPM	22.26 RPM
SRP007412_kidney	0.37 RPM	74.74 RPM
SRP007412_liver	0.00 RPM	47.11 RPM
SRP007412_testis	0.21 RPM	128.15 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1020 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1020 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1304
Pan troglodytes	retro_ptro_894

---

Parental genes homology:

Parental genes homology involve 21 parental genes, and 82 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000016025	8 retrocopies	retro_cfam_1057, retro_cfam_1131, retro_cfam_1134, retro_cfam_1300, retro_cfam_1412, retro_cfam_1803, retro_cfam_2063, retro_cfam_2127,
Choloepus hoffmanni	ENSCHOG00000008727	3 retrocopies	retro_chof_1245, retro_chof_482, retro_chof_573,
Callithrix jacchus	ENSCJAG00000013573	4 retrocopies	retro_cjac_1107, retro_cjac_2109, retro_cjac_50, retro_cjac_854,
Felis catus	ENSFCAG00000009646	2 retrocopies	retro_fcat_234, retro_fcat_513,
Homo sapiens	ENSG00000073584	5 retrocopies	retro_hsap_1195, retro_hsap_1304, retro_hsap_3623, retro_hsap_3947, retro_hsap_922,
Gorilla gorilla	ENSGGOG00000011803	2 retrocopies	retro_ggor_1020 , retro_ggor_931,
Microcebus murinus	ENSMICG00000009821	4 retrocopies	retro_mmur_1408, retro_mmur_1592, retro_mmur_608, retro_mmur_928,
Myotis lucifugus	ENSMLUG00000004609	1 retrocopy	retro_mluc_1209,
Macaca mulatta	ENSMMUG00000004005	3 retrocopies	retro_mmul_1284, retro_mmul_2159, retro_mmul_2286,
Mustela putorius furo	ENSMPUG00000014660	4 retrocopies	retro_mputfur_1411, retro_mputfur_1482, retro_mputfur_1499, retro_mputfur_739,
Mus musculus	ENSMUSG00000037935	5 retrocopies	retro_mmus_1111, retro_mmus_1127, retro_mmus_2437, retro_mmus_2618, retro_mmus_3194,
Nomascus leucogenys	ENSNLEG00000001957	4 retrocopies	retro_nleu_1060, retro_nleu_2051, retro_nleu_2083, retro_nleu_286,
Oryctolagus cuniculus	ENSOCUG00000008981	1 retrocopy	retro_ocun_59,
Otolemur garnettii	ENSOGAG00000001652	7 retrocopies	retro_ogar_1734, retro_ogar_2059, retro_ogar_3199, retro_ogar_402, retro_ogar_454, retro_ogar_682, retro_ogar_760,
Ochotona princeps	ENSOPRG00000000985	1 retrocopy	retro_opri_731,
Pongo abelii	ENSPPYG00000008456	4 retrocopies	retro_pabe_2973, retro_pabe_3251, retro_pabe_794, retro_pabe_994,
Pan troglodytes	ENSPTRG00000022902	5 retrocopies	retro_ptro_2451, retro_ptro_2678, retro_ptro_3039, retro_ptro_639, retro_ptro_894,
Pteropus vampyrus	ENSPVAG00000011355	1 retrocopy	retro_pvam_237,
Rattus norvegicus	ENSRNOG00000010676	7 retrocopies	retro_rnor_1278, retro_rnor_1311, retro_rnor_1456, retro_rnor_1507, retro_rnor_1599, retro_rnor_2383, retro_rnor_2593,
Tupaia belangeri	ENSTBEG00000000770	10 retrocopies	retro_tbel_1246, retro_tbel_1554, retro_tbel_2208, retro_tbel_2955, retro_tbel_4035, retro_tbel_4629, retro_tbel_4656, retro_tbel_658, retro_tbel_821, retro_tbel_844,
Tursiops truncatus	ENSTTRG00000013885	1 retrocopy	retro_ttru_1217,