RetrogeneDB ID: retro_cpor_517

Retrocopy location

• Organism: Guinea Pig (Cavia porcellus)
• Coordinates: scaffold_18:6741006..6741434(+)
• Located in intron of: ENSCPOG00000001117

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: C14ORF166
• Ensembl ID: ENSCPOG00000001317
• Aliases: None
• Description: None

Sequence

>retro_cpor_517
CTGATGGCTCTCGACTACCACAACCTTGCTGGCTTCAACTGCAAAGACGAAGCAGAATTTAGAGGCTTTATTGTTTGGTT
GAAGACCAGAAAATCAGACACTGAAAGACTGAAGACAGAGGTAATTTAAAAAACATCTCCAGCAGTGACTGGCTCAAGTT
CTTTTAAAAGTGTCTCAGAAATGTTGGCTGTCCTTTCAAGATTCAGGATCTACATGAAGCAATTGACTGGTTCCTTGGCT
TAGCTGTTAGACTTGAATATGGGGATAATGCTAAAAAATACAAGGACTTAACACCTGACAATGCAAAAAATACTGACAAT
GCAACTGAAAATGTAGACCCACTGATCAGTTTGGATGTAAATAATCCCAGTTTTAAGACCGGTGTAATGGCTTTGGCTAA
CCTCCCTCGGGTTAAGCACCATGATAAT

Alignment

ORF - retro_cpor_517 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.47 %
• Parental protein coverage: 58.61 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  LTALDYHNPAGFNCKDETEFRNFIVWL-EDQKIRHYKIEDRGNLRNIPSSDWPKFFEKYLRDVDCPFKIQ
          L.ALDYHN.AGFNCKDE.EFR.FIVWL.EDQKIRH.K.EDRGNL.NI.SSDW.KFF.K.LR.V.CPFKIQ
Retrocopy LMALDYHNLAGFNCKDEAEFRGFIVWL<EDQKIRH*KTEDRGNLKNISSSDWLKFF*KCLRNVGCPFKIQ

Parental  DRQEAIDWLLGLAVRLEYGDNAEKYKDLTPDNAKNIDNATKNAEPLINLDVNNPDFKAGVMALANLLQIQ
          D..EAIDW.LGLAVRLEYGDNA.KYKDLTPDNAKN.DNAT.N..PLI.LDVNNP.FK.GVMALANL....
Retrocopy DLHEAIDWFLGLAVRLEYGDNAKKYKDLTPDNAKNTDNATENVDPLISLDVNNPSFKTGVMALANLPRVK

Parental  RHDD
          .HD.
Retrocopy HHDN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	39.40 RPM
SRP017611_kidney	0.10 RPM	97.57 RPM
SRP017611_liver	0.00 RPM	84.09 RPM
SRP040447_lung	0.00 RPM	61.31 RPM
SRP040447_skeletal_muscle	0.00 RPM	104.77 RPM

ChIP-Seq

Cavia porcellus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cpor_517 retrocopy.

TSS

Cavia porcellus was not studied using FANTOM5 data.

Lab

retro_cpor_517 was not experimentally validated.

Homology

Retrocopy orthology:

Cavia porcellus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 29 parental genes, and 70 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000002083	2 retrocopies	retro_amel_224, retro_amel_302,
Canis familiaris	ENSCAFG00000014648	4 retrocopies	retro_cfam_1025, retro_cfam_2042, retro_cfam_237, retro_cfam_734,
Callithrix jacchus	ENSCJAG00000006926	3 retrocopies	retro_cjac_1262, retro_cjac_1947, retro_cjac_3207,
Cavia porcellus	ENSCPOG00000001317	6 retrocopies	retro_cpor_1041, retro_cpor_1177, retro_cpor_1239, retro_cpor_1247, retro_cpor_517 , retro_cpor_541,
Dasypus novemcinctus	ENSDNOG00000003248	3 retrocopies	retro_dnov_458, retro_dnov_572, retro_dnov_609,
Dipodomys ordii	ENSDORG00000012335	1 retrocopy	retro_dord_619,
Equus caballus	ENSECAG00000012600	1 retrocopy	retro_ecab_483,
Erinaceus europaeus	ENSEEUG00000015583	1 retrocopy	retro_eeur_366,
Felis catus	ENSFCAG00000002663	3 retrocopies	retro_fcat_1160, retro_fcat_1415, retro_fcat_948,
Homo sapiens	ENSG00000087302	1 retrocopy	retro_hsap_2307,
Loxodonta africana	ENSLAFG00000003162	1 retrocopy	retro_lafr_301,
Microcebus murinus	ENSMICG00000008720	1 retrocopy	retro_mmur_857,
Myotis lucifugus	ENSMLUG00000008643	6 retrocopies	retro_mluc_1228, retro_mluc_1518, retro_mluc_1834, retro_mluc_2610, retro_mluc_456, retro_mluc_676,
Macaca mulatta	ENSMMUG00000018200	2 retrocopies	retro_mmul_1045, retro_mmul_2025,
Monodelphis domestica	ENSMODG00000013211	1 retrocopy	retro_mdom_1296,
Mustela putorius furo	ENSMPUG00000005253	6 retrocopies	retro_mputfur_1333, retro_mputfur_1421, retro_mputfur_203, retro_mputfur_328, retro_mputfur_655, retro_mputfur_797,
Mus musculus	ENSMUSG00000021807	2 retrocopies	retro_mmus_140, retro_mmus_3203,
Nomascus leucogenys	ENSNLEG00000012406	1 retrocopy	retro_nleu_2749,
Oryctolagus cuniculus	ENSOCUG00000014681	1 retrocopy	retro_ocun_221,
Otolemur garnettii	ENSOGAG00000013232	5 retrocopies	retro_ogar_1060, retro_ogar_1856, retro_ogar_2351, retro_ogar_2976, retro_ogar_3192,
Ochotona princeps	ENSOPRG00000016352	2 retrocopies	retro_opri_257, retro_opri_884,
Pongo abelii	ENSPPYG00000005814	1 retrocopy	retro_pabe_1980,
Pan troglodytes	ENSPTRG00000006344	1 retrocopy	retro_ptro_1631,
Pteropus vampyrus	ENSPVAG00000013392	1 retrocopy	retro_pvam_1088,
Sus scrofa