RetrogeneDB ID: retro_rnor_1986

Retrocopy location

• Organism: Rat (Rattus norvegicus)
• Coordinates: 4:151029368..151029861(+)
• Located in intron of: ENSRNOG00000012337

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Apoo
• Ensembl ID: ENSRNOG00000046918
• Aliases: Apoo, RGD1565289
• Description: apolipoprotein O [Source:RefSeq peptide;Acc:NP_001186107]

Sequence

>retro_rnor_1986
AAAAGTTACATGAAGATCGATGAGCTTTCACTCTACTCAGTTCCTGAGAGTCAGTCTAAATATGTGGAGGAGCCAAGGAC
TCAACTTGAAGAAAACATCTCACAACTCCGATATCGTTGTGAGCCATATACAAGTTTGTGTCAGGAAATATACTCCCATA
CTAAGCTCAAGGTGGAACACTTTGTCCAGTGAGGGGTAGACAACTATAACTATCTTCAAAATATGCCTCCTGGATTGTCC
CCAAGACTTGGTGTTATTGGTTCTGCTTGTTTGTTGGACTCCTTTTTGCTAGAGGTTCAAAAATAAAGAATCTGGTGTAT
CCTTCTTTTTTCATGGGACTAGGTGCCTCTGTCTATTACCACATCTACAAGGCATCACCATTGCCCAGATCCCTGGGGAG
AAGTTATATGGCTGGGTATTATGAGGGTACATAGATTTGTGGAAGCAAAATTTTCAGAAGCCAGGCAATATGAAGAATTC
ACCTGAAAATAAA

Alignment

ORF - retro_rnor_1986 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.24 %
• Parental protein coverage: 84.34 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  KSYMKIDELSLYSVPEGQSKYVEEPRTQLEENISELRHRCEPYTNLCQEIYSHTKPKVEHFVQWGVDNYN
          KSYMKIDELSLYSVPE.QSKYVEEPRTQLEENIS.LR.RCEPYT.LCQEIYSHTK.KVEHFVQ.GVDNYN
Retrocopy KSYMKIDELSLYSVPESQSKYVEEPRTQLEENISQLRYRCEPYTSLCQEIYSHTKLKVEHFVQ*GVDNYN

Parental  YLQNAPPGFYPRLGVIG-FAGFVGLLFARGSKIKKLVYPPF-FMGLGASVYYPQ-QAITIAQITGEKLYD
          YLQN.PPG..PRLGVIG.F..FVGLLFARGSKIK.LVYP.F.F.G.......P..Q.ITIAQI.GEKLY.
Retrocopy YLQNMPPGLSPRLGVIG<FCLFVGLLFARGSKIKNLVYPSF<FHGTRCLCLLPHLQGITIAQIPGEKLYG

Parental  WGLRGYIVVEDLWKQHFQKPGNVKSSPGNK
          W.L.GYI...DLWKQ.FQKPGN.K.SP.NK
Retrocopy WVL*GYI---DLWKQNFQKPGNMKNSPENK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	13.52 RPM
SRP017611_kidney	0.00 RPM	32.31 RPM
SRP017611_liver	0.00 RPM	5.51 RPM

ChIP-Seq

Rattus norvegicus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_rnor_1986 retrocopy.

TSS

Rattus norvegicus was not studied using FANTOM5 data.

Lab

retro_rnor_1986 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_rnor_1986 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000012749	1 retrocopy	retro_amel_1282,
Choloepus hoffmanni	ENSCHOG00000000226	2 retrocopies	retro_chof_2372, retro_chof_839,
Callithrix jacchus	ENSCJAG00000004909	8 retrocopies	retro_cjac_1360, retro_cjac_1417, retro_cjac_1448, retro_cjac_1767, retro_cjac_1792, retro_cjac_1896, retro_cjac_2038, retro_cjac_2063,
Cavia porcellus	ENSCPOG00000004197	1 retrocopy	retro_cpor_309,
Dasypus novemcinctus	ENSDNOG00000006710	1 retrocopy	retro_dnov_2450,
Equus caballus	ENSECAG00000013441	1 retrocopy	retro_ecab_145,
Echinops telfairi	ENSETEG00000014150	3 retrocopies	retro_etel_1052, retro_etel_516, retro_etel_711,
Felis catus	ENSFCAG00000000029	3 retrocopies	retro_fcat_1203, retro_fcat_1657, retro_fcat_1798,
Loxodonta africana	ENSLAFG00000029070	1 retrocopy	retro_lafr_1114,
Macropus eugenii	ENSMEUG00000014222	1 retrocopy	retro_meug_700,
Macaca mulatta	ENSMMUG00000016361	4 retrocopies	retro_mmul_1584, retro_mmul_1886, retro_mmul_2051, retro_mmul_814,
Monodelphis domestica	ENSMODG00000025554	1 retrocopy	retro_mdom_1510,
Mustela putorius furo	ENSMPUG00000000109	1 retrocopy	retro_mputfur_109,
Mus musculus	ENSMUSG00000079508	1 retrocopy	retro_mmus_282,
Otolemur garnettii	ENSOGAG00000001960	6 retrocopies	retro_ogar_1083, retro_ogar_1104, retro_ogar_2092, retro_ogar_2466, retro_ogar_2927, retro_ogar_3094,
Pteropus vampyrus	ENSPVAG00000002530	2 retrocopies	retro_pvam_128, retro_pvam_594,
Rattus norvegicus	ENSRNOG00000046918	4 retrocopies	retro_rnor_1022, retro_rnor_1986 , retro_rnor_2096, retro_rnor_2308,
Sarcophilus harrisii	ENSSHAG00000008734	1 retrocopy	retro_shar_125,
Sus scrofa	ENSSSCG00000012174	1 retrocopy	retro_sscr_774,
Tupaia belangeri	ENSTBEG00000014888	6 retrocopies	retro_tbel_1153, retro_tbel_4004, retro_tbel_4261, retro_tbel_4698, retro_tbel_715, retro_tbel_96,