RetrogeneDB ID: retro_ogar_1375

Retrocopy location

• Organism: Bushbaby (Otolemur garnettii)
• Coordinates: GL873544.1:1764539..1765167(-)
• Located in intron of: ENSOGAG00000016921

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: EIF4A1
• Ensembl ID: ENSOGAG00000008132
• Aliases: None
• Description: eukaryotic translation initiation factor 4A1 [Source:HGNC Symbol;Acc:3282]

Sequence

>retro_ogar_1375
ATTGTTGATAGCTTTGATGTCCTAAACCTCATGGAGCCCCTCCTTTGTGGCATCTATGCCTATGGTTTTGAGAAGCCCTC
TGCCATCCAGCAATGAGCTATTTTTCCTTGTTTCAGGGTTATAAATGTAATCTCTCAAGCCTGGCCTGGGACGAGAGAAT
GGCCACATTTGCCATATCAATCCTGCAGCAGATTTAATTGGCTCTAATGGCCACCCAGGCTTTGGTACTAGTACCCACTC
AAGAATTGGCTCAGCAGATACAGAAGGTGGTCATGGCATTAGGAAACTATATGGCTGTCTCCTGTCATGCCTGCATTGGG
GATACCAACATGCATTCCAAAGAGCAGAGCTGTAGATAGAAGCTCCCCATGTCATTCTTGGTATGCCTGGCCAAGTATTT
GACAGGCTTATCTGGAGATACCTGTCTCCCAGATATATCGAGATATTTGTACTGGATGAAACTGATGAAATGTTAACCCG
TGGATTCAATAACCAGGTCTATGAAATATTCCAAAAACTCAAAATCAACACCCAGGTAGTTTGGCTACCAGCTACAATGC
CTTCCGACATGCTTGAGGTGACCAAGAAGTTCATGAGGTACCTCATTCAGATTCCTGTCAAGAAGGAA

Alignment

ORF - retro_ogar_1375 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 70.75 %
• Parental protein coverage: 51.47 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  IVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTG-KTATFAISILQQIELDL
          IVDSFD..NL.E.LL.GIYAYGFEKPSAIQQ.AI.PC.....VI.QA..GT....ATFAISILQQI.L.L
Retrocopy IVDSFDVLNLMEPLLCGIYAYGFEKPSAIQQ*AIFPCFRVINVISQAWPGTR<RMATFAISILQQI*LAL

Parental  KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQ-KLQMEAPHIIVGTPGRVFDMLN
          .ATQALVL.PT.ELAQQIQKVVMALG.YM..SCHACIG.TN.....Q..L..EAPH.I.G.PG.VFD.L.
Retrocopy MATQALVLVPTQELAQQIQKVVMALGNYMAVSCHACIGDTNMHSKEQ<EL*IEAPHVILGMPGQVFDRLI

Parental  RRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVK
          .RYLSP.YI..FVLDE.DEML.RGF..Q.Y.IFQKL..NTQVV.L.ATMPSD.LEVTKKFMR..I.I.VK
Retrocopy WRYLSPRYIEIFVLDETDEMLTRGFNNQVYEIFQKLKINTQVVWLPATMPSDMLEVTKKFMRYLIQIPVK

Parental  KE
          KE
Retrocopy KE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Otolemur garnettii was not studied using RNA-Seq expression data.

ChIP-Seq

Otolemur garnettii was not studied using ChIP-Seq data.

EST

Otolemur garnettii was not studied using EST data.

TSS

Otolemur garnettii was not studied using FANTOM5 data.

Lab

retro_ogar_1375 was not experimentally validated.

Homology

Retrocopy orthology:

Otolemur garnettii does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 13 parental genes, and 35 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000016753	1 retrocopy	retro_amel_1300,
Callithrix jacchus	ENSCJAG00000015114	8 retrocopies	retro_cjac_1876, retro_cjac_2046, retro_cjac_2521, retro_cjac_2679, retro_cjac_3086, retro_cjac_3203, retro_cjac_395, retro_cjac_727,
Dipodomys ordii	ENSDORG00000014225	1 retrocopy	retro_dord_732,
Macropus eugenii	ENSMEUG00000010780	2 retrocopies	retro_meug_158, retro_meug_179,
Microcebus murinus	ENSMICG00000014759	2 retrocopies	retro_mmur_1164, retro_mmur_1477,
Myotis lucifugus	ENSMLUG00000003415	3 retrocopies	retro_mluc_1047, retro_mluc_1229, retro_mluc_1805,
Macaca mulatta	ENSMMUG00000013499	1 retrocopy	retro_mmul_1280,
Monodelphis domestica	ENSMODG00000007090	3 retrocopies	retro_mdom_1282, retro_mdom_326, retro_mdom_711,
Otolemur garnettii	ENSOGAG00000007495	1 retrocopy	retro_ogar_212,
Otolemur garnettii	ENSOGAG00000008132	2 retrocopies	retro_ogar_1375 , retro_ogar_1862,
Otolemur garnettii	ENSOGAG00000010729	2 retrocopies	retro_ogar_2830, retro_ogar_943,
Ochotona princeps	ENSOPRG00000008591	2 retrocopies	retro_opri_155, retro_opri_985,
Sorex araneus	ENSSARG00000006017	7 retrocopies	retro_sara_224, retro_sara_383, retro_sara_461, retro_sara_567, retro_sara_6, retro_sara_605, retro_sara_89,