RetrogeneDB ID: retro_ocun_1575

Retrocopy location

• Organism: Rabbit (Oryctolagus cuniculus)
• Coordinates: GL018701:737816..738100(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: BLOC1S6
• Ensembl ID: ENSOCUG00000017351
• Aliases: None
• Description: biogenesis of lysosomal organelles complex-1, subunit 6, pallidin [Source:HGNC Symbol;Acc:8549]

Sequence

>retro_ocun_1575
CAGAACCAAGTTGTTTTATTAGACACACTGGAACAAGAGATTTCAGAATTTAAAGAATGTCATTCTATGTTGAACATTAA
TGCTTTCTTCACCGAAACGAAACATTTTCATGCCAAGTTGGTGAATATAAGGAAAGAGATGCTGGTGCTTCCTGAGAAGA
CATGCAAGTTAAAAAAATAGCACAGAACCTGCAGCAGAACACGCAAAAAGAGGAGTTGGAAAGGGAGCAGCAACGGGAGA
AGGGGTTTGAAAGAGAAAAGCAGTTAGCTGCCAAGCCAGCTCAA

Alignment

ORF - retro_ocun_1575 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.25 %
• Parental protein coverage: 54.6 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  QNQVVLLDTLEQEISKFKECHSMLDINALFTEAKHYHAKLVNIRKEMLMLHEKTSKL-KKRALKLQQKRQ
          QNQVVLLDTLEQEIS.FKECHSML.INA.FTE.KH.HAKLVNIRKEML.L.EKT.KL.KK.A..LQQ..Q
Retrocopy QNQVVLLDTLEQEISEFKECHSMLNINAFFTETKHFHAKLVNIRKEMLVLPEKTCKL<KKIAQNLQQNTQ

Parental  KEELEREQQREKEFEREKQLTARPAK
          KEELEREQQREK.FEREKQL.A.PA.
Retrocopy KEELEREQQREKGFEREKQLAAKPAQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	8.55 RPM
SRP017611_kidney	0.00 RPM	11.35 RPM
SRP017611_liver	0.00 RPM	2.24 RPM

ChIP-Seq

Oryctolagus cuniculus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ocun_1575 retrocopy.

TSS

Oryctolagus cuniculus was not studied using FANTOM5 data.

Lab

retro_ocun_1575 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ocun_1575 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 10 parental genes, and 21 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000012059	7 retrocopies	retro_chof_1342, retro_chof_20, retro_chof_2054, retro_chof_2102, retro_chof_211, retro_chof_248, retro_chof_600,
Dasypus novemcinctus	ENSDNOG00000019785	5 retrocopies	retro_dnov_1687, retro_dnov_1885, retro_dnov_2009, retro_dnov_2411, retro_dnov_275,
Echinops telfairi	ENSETEG00000007378	1 retrocopy	retro_etel_404,
Gorilla gorilla	ENSGGOG00000013892	1 retrocopy	retro_ggor_2983,
Macropus eugenii	ENSMEUG00000012636	1 retrocopy	retro_meug_778,
Microcebus murinus	ENSMICG00000005595	1 retrocopy	retro_mmur_1610,
Monodelphis domestica	ENSMODG00000017628	2 retrocopies	retro_mdom_1673, retro_mdom_561,
Oryctolagus cuniculus	ENSOCUG00000017351	1 retrocopy	retro_ocun_1575 ,
Otolemur garnettii	ENSOGAG00000013706	1 retrocopy	retro_ogar_206,
Pan troglodytes	ENSPTRG00000007038	1 retrocopy	retro_ptro_2949,