RetrogeneDB ID: retro_ggor_3019

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: X:60541201..60541756(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000027034
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: CBX1
• Ensembl ID: ENSGGOG00000024063
• Aliases: None
• Description: None

Sequence

>retro_ggor_3019
ATGGGGGAAAAACTAAACAAGAAGAAAGTGGAGGAAGTGCTAGAAGAGGAGGAAAAGGAATATGTGGTGGAAAAAGTTCT
CGACCATGGAGTGGTAAAGGGCAAAGTGGAGTACCTCCTAAAGTGGAAGGGATTCTCAGATGAGGATAACACATGGGAGT
CAGAAGAGAACCTGGATTGCCTCGACCTCATTGCTGAGTTTCTGCAGTCACAGAAAACAACACATGAGACAGATAAATCA
GAGGGAGGCAAGCACAAAGCTGATTCTGATTCTGAAGATAAGGGAGAGGAGAGCAAACCAAAGGAGAAGAAAGAAGAGTC
AGAAAAGCCACGAGGCTTTGCTCGAGGTTTGGAGCCAGAGCGGATTATTGGAGCTACAGACTCCAGTGGGGAGGTCATGT
TCCTGATGAAATGGAAAAACTCTGATGAGGCTGACCTGGTCCCTGCCAAGGAAGCCAGTGTCAAGTGCCCACAGGTTGTC
ATATCCTTCTATGAGGAAAGGCTGACATGGCATTCCTAACCCTCGGAGGATGATGACAAAAAAGATGACAAGAAT

Alignment

ORF - retro_ggor_3019 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 91.01 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQS
          MG.K.NKKKVEEVLEEEE.EYVVEKVLD..VVKGKVEYLLKWKGFSDEDNTWE.EENLDC.DLIAEFLQS
Retrocopy MGEKLNKKKVEEVLEEEEKEYVVEKVLDHGVVKGKVEYLLKWKGFSDEDNTWESEENLDCLDLIAEFLQS

Parental  QKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEEVRIESEKPRGFARGLEPERIIGATDSSGELMFLM
          QKT.HETDKSEGGK.KADSDSEDKGEESKPK.KKEE....SEKPRGFARGLEPERIIGATDSSGE.MFLM
Retrocopy QKTTHETDKSEGGKHKADSDSEDKGEESKPKEKKEE----SEKPRGFARGLEPERIIGATDSSGEVMFLM

Parental  KWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN
          KWKNSDEADLVPAKEA.VKCPQVVISFYEERLTWHS.PSEDDDKKDDKN
Retrocopy KWKNSDEADLVPAKEASVKCPQVVISFYEERLTWHS*PSEDDDKKDDKN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	2.21 RPM	69.63 RPM
SRP007412_cerebellum	2.13 RPM	66.98 RPM
SRP007412_heart	0.44 RPM	13.79 RPM
SRP007412_kidney	0.49 RPM	47.55 RPM
SRP007412_liver	0.18 RPM	17.28 RPM
SRP007412_testis	3.94 RPM	176.84 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_3019 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_3019 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4840

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 77 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000004890	2 retrocopies	retro_amel_1228, retro_amel_54,
Canis familiaris	ENSCAFG00000016832	1 retrocopy	retro_cfam_804,
Choloepus hoffmanni	ENSCHOG00000011957	2 retrocopies	retro_chof_1860, retro_chof_2185,
Callithrix jacchus	ENSCJAG00000007532	2 retrocopies	retro_cjac_191, retro_cjac_51,
Felis catus	ENSFCAG00000006056	1 retrocopy	retro_fcat_514,
Homo sapiens	ENSG00000108468	3 retrocopies	retro_hsap_4654, retro_hsap_4790, retro_hsap_4840,
Gorilla gorilla	ENSGGOG00000000041	1 retrocopy	retro_ggor_1955,
Gorilla gorilla	ENSGGOG00000024063	3 retrocopies	retro_ggor_2887, retro_ggor_3019 , retro_ggor_330,
Gorilla gorilla	ENSGGOG00000025853	6 retrocopies	retro_ggor_1928, retro_ggor_2281, retro_ggor_2466, retro_ggor_2467, retro_ggor_635, retro_ggor_845,
Microcebus murinus	ENSMICG00000009510	4 retrocopies	retro_mmur_1324, retro_mmur_178, retro_mmur_467, retro_mmur_999,
Mustela putorius furo	ENSMPUG00000015302	1 retrocopy	retro_mputfur_1457,
Nomascus leucogenys	ENSNLEG00000002435	4 retrocopies	retro_nleu_1089, retro_nleu_1105, retro_nleu_1955, retro_nleu_2961,
Oryctolagus cuniculus	ENSOCUG00000008021	3 retrocopies	retro_ocun_177, retro_ocun_442, retro_ocun_55,
Procavia capensis	ENSPCAG00000002381	2 retrocopies	retro_pcap_134, retro_pcap_308,
Pongo abelii	ENSPPYG00000008891	1 retrocopy	retro_pabe_78,
Sarcophilus harrisii	ENSSHAG00000008192	1 retrocopy	retro_shar_76,
Sus scrofa	ENSSSCG00000017529	1 retrocopy	retro_sscr_635,
Tupaia belangeri	ENSTBEG00000014931	39 retrocopies	retro_tbel_1388, retro_tbel_1557, retro_tbel_1613, retro_tbel_1655, retro_tbel_1663, retro_tbel_1794, retro_tbel_2124, retro_tbel_2130, retro_tbel_2281, retro_tbel_2313, retro_tbel_2346, retro_tbel_2539, retro_tbel_2559, retro_tbel_2571, retro_tbel_2587, retro_tbel_270, retro_tbel_2713, retro_tbel_2716, retro_tbel_2752, retro_tbel_2809, retro_tbel_2835, retro_tbel_2854, retro_tbel_2926, retro_tbel_2993, retro_tbel_303, retro_tbel_3236, retro_tbel_3370, retro_tbel_3685, retro_tbel_3998, retro_tbel_4032, retro_tbel_4202, retro_tbel_4611, retro_tbel_4630, retro_tbel_484, retro_tbel_558, retro_tbel_687, retro_tbel_792, retro_tbel_793, retro_tbel_938,