RetrogeneDB ID: retro_fcat_1693

Retrocopy location

• Organism: Cat (Felis catus)
• Coordinates: E2:46547526..46548062(+)
• Located in intron of: ENSFCAG00000002652

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MEST
• Ensembl ID: ENSFCAG00000022984
• Aliases: None
• Description: mesoderm specific transcript [Source:HGNC Symbol;Acc:7028]

Sequence

>retro_fcat_1693
ATGAAGGAGTGGTGGGTTCAGGTGGGGTGACTAGCCGTGCCCCTGTTTGTGGCCTATCTGTGTTTCCCGGCACTCCAGCT
GTCTCCTGCTCTTCACTCGTGGAAGTCGTCAGGCAGATTTTTCACCTACGAGAGACTGCACATCTTCTACCAGGACTCTG
TGGGTGTGGTTGGAAATCCTGAGATAGTTGTGCCTTTACCTAGGTTTCCAACTTCCAGCTGTGATTAGTACAAGATTTGG
GAAGGTCTGACCGTGAGGTTTTAACGAGTGATTGCCCTGGGTTTCTTGGTCTTTGGTCGCAGTGACAAACGAGACCACAT
CACTGTTCCATATTTGAGCAGGCCAGCATCATAGAGGCATTTTTGTGGCATCTGGGGCTCCAGAACCATAGGATCAACCT
TTTGTCTCATGATTACAGAGGTATCGTTGCTCAGAAGGTGCTCTATAGGTTCGAGCAGAAATGATCTTGTCAGCTTACCG
TGAGGAGTCTCTATCTGTCAAATGGAGGTATATTTCCTGAGATTCACCGTCCTCTC

Alignment

ORF - retro_fcat_1693 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 76.11 %
• Parental protein coverage: 54.91 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MREWWVQVGLLAVPLLAAYLHIPPPQLSPALHSWKSSGKFFTYKGLRIFYQDSVGVVGSPEIVVLLHGFP
          M.EWWVQVG.LAVPL..AYL..P..QLSPALHSWKSSG.FFTY..L.IFYQDSVGVVG.PEIVV.L..FP
Retrocopy MKEWWVQVG*LAVPLFVAYLCFPALQLSPALHSWKSSGRFFTYERLHIFYQDSVGVVGNPEIVVPLPRFP

Parental  TSSYDWYKIWEGLTLRFHRVIALDFLGFGFSDK-PRPHHYSIFEQASIVEALLRHLGLQNRRINLLSHDY
          TSS.D.YKIWEGLT.RF.RVIAL.FL.FG.SDK..RPHH.SIFEQASI.EA.L.HLGLQN.RINLLSHDY
Retrocopy TSSCD*YKIWEGLTVRF*RVIALGFLVFGRSDK<TRPHHCSIFEQASIIEAFLWHLGLQNHRINLLSHDY

Parental  GDIVAQELLYRFKQNRSGRLTIKSLCLSNGGIFPETHRPL
          ..IVAQ..LYRF.Q..S..LT..SL.LSNGGIFPE.HRPL
Retrocopy RGIVAQKVLYRFEQK*SCQLTVRSLYLSNGGIFPEIHRPL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	38.10 RPM
SRP017611_kidney	0.00 RPM	7.01 RPM
SRP017611_liver	0.00 RPM	2.63 RPM

ChIP-Seq

Felis catus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_fcat_1693 retrocopy.

TSS

Felis catus was not studied using FANTOM5 data.

Lab

retro_fcat_1693 was not experimentally validated.

Homology

Retrocopy orthology:

Felis catus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 15 parental genes, and 35 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000005659	2 retrocopies	retro_amel_1177, retro_amel_1874,
Callithrix jacchus	ENSCJAG00000010760	2 retrocopies	retro_cjac_1563, retro_cjac_3931,
Felis catus	ENSFCAG00000022984	5 retrocopies	retro_fcat_1067, retro_fcat_1645, retro_fcat_1693 , retro_fcat_2004, retro_fcat_326,
Loxodonta africana	ENSLAFG00000006066	3 retrocopies	retro_lafr_578, retro_lafr_584, retro_lafr_748,
Macropus eugenii	ENSMEUG00000008227	1 retrocopy	retro_meug_885,
Microcebus murinus	ENSMICG00000006129	1 retrocopy	retro_mmur_1091,
Macaca mulatta	ENSMMUG00000009499	2 retrocopies	retro_mmul_1936, retro_mmul_94,
Nomascus leucogenys	ENSNLEG00000012841	3 retrocopies	retro_nleu_1065, retro_nleu_515, retro_nleu_790,
Otolemur garnettii	ENSOGAG00000009224	1 retrocopy	retro_ogar_3464,
Pongo abelii	ENSPPYG00000018006	4 retrocopies	retro_pabe_2337, retro_pabe_2510, retro_pabe_2511, retro_pabe_866,
Pan troglodytes	ENSPTRG00000019698	2 retrocopies	retro_ptro_1769, retro_ptro_2045,
Sorex araneus	ENSSARG00000000502	1 retrocopy	retro_sara_352,
Ictidomys tridecemlineatus	ENSSTOG00000020977	2 retrocopies	retro_itri_1210, retro_itri_1610,
Tupaia belangeri	ENSTBEG00000008404	2 retrocopies	retro_tbel_1480, retro_tbel_526,
Tursiops truncatus	ENSTTRG00000004934	4 retrocopies	retro_ttru_1026, retro_ttru_1115, retro_ttru_1133, retro_ttru_1907,