RetrogeneDB ID: retro_chof_760

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_144123:4966..5694(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ATF1
• Ensembl ID: ENSCHOG00000004733
• Aliases: None
• Description: activating transcription factor 1 [Source:HGNC Symbol;Acc:783]

Sequence

>retro_chof_760
CACGCACCACACATGCAAACGGCATCATCCTTATCAGAAAGTGAGGAGTGGGACTCATCTGACAGCAGAGGCTCCTCACA
GAAAACCCACGGGATTCTAGCACGGTGCCCATCTCACAGAAAAATTCTGAAAGACCTGTCTTCTAAAGATATACAGGGCA
GAAAAGGAGACGGAGAAAACCATGGAGTCTCTACTGTCACTTGTCTGTCTCTTCCAACTTCCATCTGTCAGACTAGCCAG
TACATTGCTATTGCCCCAAATGGAGCCTTTCAGCGGCCAGTCCAGGCACATATGGAGTACAGGGACTTCAGACATTAACC
ATGACAAATTCAGGCAGTACTCAGGAAGGAACAATAATTCTCCAGTATGCAGAGACCTCAGATGGACAGCAAATACTTGT
GCCCAGCAACCAGATGGTTGTACAGACTGCGTGAGGAGATATGTAGACATATCAGATGTGTATCACACCCACCATTACTT
CGCTGCCACAAACTGCAGTAATGACATCGCCTGTGAATCTTCCATCTCAAACAGCTAAAGCAGATGAACCCTAATTGAAA
AGAGAGATAAGATTAATGAAAAACAGAGAAGCTGCTTGAGAATGTCACAGAAAGAAGAAAGAATATGTGAAATGCCTGGA
AAATCAAGTTGCAGTCTTGGAAAATCAAAATAAAACTTTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCCATA
AAAGTGTT

Alignment

ORF - retro_chof_760 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.53 %
• Parental protein coverage: 91.51 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  HISHIAQQASSLSESEESQDSSDSIGSSQKTHGILARRPSYRKILKDLSSEDIRGRKGDGENPGVSTVTS
          H..H..Q.ASSLSESEE..DSSDS.GSSQKTHGILAR.PS.RKILKDLSS.DI.GRKGDGEN.GVSTVT.
Retrocopy HAPHM-QTASSLSESEE-WDSSDSRGSSQKTHGILARCPSHRKILKDLSSKDIQGRKGDGENHGVSTVTC

Parental  MSVPTPIYQTSTGQYIAIAPNGALQ-LASPGTDGVQGLQTLTMTNSGSSQQGTTTILQYAQTSDGQQILV
          .S.PT.I.QTS..QYIAIAPNGA.Q..ASPGT.GVQGLQTLTMTNSGS.Q.GT..ILQYA.TSDGQQILV
Retrocopy LSLPTSICQTS--QYIAIAPNGAFQ<AASPGTYGVQGLQTLTMTNSGSTQEGTI-ILQYAETSDGQQILV

Parental  PSNQVVVQTASGDMQTYQIRTTPTASSLPQTVVMTSPVNLTSQTTKTDDPQLKREIRLMKNREAARECRR
          PSNQ.VVQTA.GDM.TYQ...TPT..SLPQT.VMTSPVNL.SQT.K.D.P.LKREIRLMKNREAA.EC.R
Retrocopy PSNQMVVQTA*GDM*TYQMCITPTITSLPQTAVMTSPVNLPSQTAKADEP*LKREIRLMKNREAA*ECHR

Parental  KKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSHKSV
          KKKEYVKCLEN.VAVLENQNKTLIEELKTLKDLYSHKSV
Retrocopy KKKEYVKCLENQVAVLENQNKTLIEELKTLKDLYSHKSV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_760 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 9 parental genes, and 16 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000004733	5 retrocopies	retro_chof_1987, retro_chof_2305, retro_chof_27, retro_chof_462, retro_chof_760 ,
Erinaceus europaeus	ENSEEUG00000008000	2 retrocopies	retro_eeur_332, retro_eeur_704,
Felis catus	ENSFCAG00000013892	1 retrocopy	retro_fcat_1284,
Homo sapiens	ENSG00000123268	1 retrocopy	retro_hsap_3633,
Microcebus murinus	ENSMICG00000003301	1 retrocopy	retro_mmur_1336,
Mus musculus	ENSMUSG00000023027	1 retrocopy	retro_mmus_3609,
Oryctolagus cuniculus	ENSOCUG00000017023	1 retrocopy	retro_ocun_383,
Procavia capensis	ENSPCAG00000010038	2 retrocopies	retro_pcap_303, retro_pcap_442,
Sarcophilus harrisii	ENSSHAG00000004637	2 retrocopies	retro_shar_221, retro_shar_635,