RetrogeneDB ID: retro_ptro_848

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 13:18240235..18241034(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: GXYLT1
• Ensembl ID: ENSPTRG00000004836
• Aliases: GXYLT1, GLT8D3
• Description: None

Sequence

>retro_ptro_848
TGTCTGGCCTGCGGCTTCTGCTCGCTCCTTTACGCCTTCAGCCAGCTCCCCATGTCCCTGGAGGAAGCAGCAGGCGGTGG
TGGCGGGAAGCAGCAGGCCTCAGTGGCTTCCTGGCTGGCAGGAGGCGGATGCGGTGCCGTGAGAGGCGCGGGCAGCGCTG
GTCCCGCTGTGCATCCTGGTGGGTGGGACAGGTGTAGTCTGAAAATACAGGCTGTTGAGAAAATGCATCTAGCTGTAGTT
GCCTGTGGTGAAAGACTGGAAGAAACTATGACCATGTTGAAGTCAGCTATCATTTTCAGGATCAAAGCTCTTCAATTCCA
GGTTTTTGCTGAAGATCAGCTACATCATAGCTTTAAAGGAAGACGTGACAGGGGTCATTTCTGCAAATATTTAATTATAC
AATATACCCCATAACCTTTCCAAGTGAGAATGCATCAGCATGGAAAAACTCTTTAAACCATGTGGTCCGCAGAGATTGTT
CTTGCCGTTATTCCTGAAAGAAGTTGACTCCCAAACTAATAGCCTTTTTTACGACCAGTTGATCATATTTGTTCTTTACT
AAAGAAATTTAATTCCACATAAATTGCTCCAGTGGCCTCAGAACACAAGGAACCTCAAATAAGATGGTATAGTCGCTTTG
CTAGGCAACCATACTGTGGAAAAACTGGAGTAAACCCTGGAGTTATGTTGACGAATATGACTCGAATGAGAAGGAAGTAT
TTCAAGAATGATATGACAAACTGTGTGACTACAATGAGGAGATATACTTATGACATGGCTTAAAGAATACAAACTAAAC

Alignment

ORF - retro_ptro_848 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.27 %
• Parental protein coverage: 66.26 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  CVACGFCSLLYAFSQLAVSLEEGAGGGGGKPQAAVASWLAGGGRGAVRGAGVAGPAAHPGVSDRYSLKIQ
          C.ACGFCSLLYAFSQL..SLEE.AGGGGGK.QA.VASWLAGGG.GAVRGAG.AGPA.HPG..DR.SLKIQ
Retrocopy CLACGFCSLLYAFSQLPMSLEEAAGGGGGKQQASVASWLAGGGCGAVRGAGSAGPAVHPGGWDRCSLKIQ

Parental  PVEKMHLAVVACGERLEETMTMLKSAIIFSIKPLQFHIFAEDQLHHSFKGRLD-NWSFLQTFNYTLYPIT
          .VEKMHLAVVACGERLEETMTMLKSAIIF.IK.LQF..FAEDQLHHSFKGR.D...SFLQ.FNYT.YPIT
Retrocopy AVEKMHLAVVACGERLEETMTMLKSAIIFRIKALQFQVFAEDQLHHSFKGRRD<QGSFLQIFNYTIYPIT

Parental  FPSENAAEWK-KLFKPCASQRLFLPLILKEVDSLLYVDTDILF-LRPVDDIWSLLKKFNSTQIAAMAPEH
          FPSENA..WK.KLFKPC..QRLFLPL.LKEVDS.....T..LF.LRPVD.I.SLLKKFNST.IA..A.EH
Retrocopy FPSENASAWK<KLFKPCGPQRLFLPLFLKEVDS----QTNSLF<LRPVDHICSLLKKFNST*IAPVASEH

Parental  EEPRIGWYNRFARHPYYGKTGVNSGVMLMNMTRMRRKYFKNDMT-TVRLQWGDILMPLLKKYKLN
          .EP.I.WY.RFAR.PY.GKTGVN.GVML.NMTRMRRKYFKNDMT.TV.LQ.GDILM..LK.YKLN
Retrocopy KEPQIRWYSRFARQPYCGKTGVNPGVMLTNMTRMRRKYFKNDMT>TV*LQ*GDILMTWLKEYKLN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	6.01 RPM
SRP007412_cerebellum	0.00 RPM	13.59 RPM
SRP007412_heart	0.00 RPM	7.29 RPM
SRP007412_kidney	0.00 RPM	15.25 RPM
SRP007412_liver	0.00 RPM	10.31 RPM
SRP007412_testis	0.00 RPM	18.55 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_848 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_848 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_848 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 8 parental genes, and 19 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000151233	5 retrocopies	retro_hsap_2295, retro_hsap_4167, retro_hsap_4177, retro_hsap_4258, retro_hsap_4267,
Gorilla gorilla	ENSGGOG00000027928	3 retrocopies	retro_ggor_1702, retro_ggor_1950, retro_ggor_2798,
Monodelphis domestica	ENSMODG00000008913	1 retrocopy	retro_mdom_512,
Mus musculus	ENSMUSG00000036197	1 retrocopy	retro_mmus_2325,
Nomascus leucogenys	ENSNLEG00000017947	1 retrocopy	retro_nleu_2700,
Pongo abelii	ENSPPYG00000004419	2 retrocopies	retro_pabe_1849, retro_pabe_1976,
Pan troglodytes	ENSPTRG00000004836	5 retrocopies	retro_ptro_1623, retro_ptro_2832, retro_ptro_2960, retro_ptro_3006, retro_ptro_848 ,
Rattus norvegicus	ENSRNOG00000005234	1 retrocopy	retro_rnor_2754,