RetrogeneDB ID: retro_ggor_2663

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 8:63563885..63564378(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000027263
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSGGOG00000027442
• Aliases: None
• Description: Peptidyl-prolyl cis-trans isomerase [Source:UniProtKB/TrEMBL;Acc:G3S3X1]

Sequence

>retro_ggor_2663
ATGGTCAACCCCACCATGTTCTTCCACATTGCCATCAATGGTGAGCCCTTGGGCCATGCCTCCTTGGAGCTGTTTGCAGA
CATGTTTTCAAAGTCAGCCAAAAACTTTCATGCTCTGAGCACTAGAGAGAAAGAATGTGGTTATAAGGTTTCCTGCTTTC
ACAAAATTATTCCAGGATGTATGTGTCAGGGTGTTGACTTCACATGCCATAATGGCACTGATGGCAAGTCCGTCTACAGG
GAGAAATTTGATGATGACAACTTCAACCTGAAGCATACACATCCTGGCATTTTGCCATGGCAATTGCTGGACCCAACACA
AACCATTCCCAGTTTTTCATCTCTGCACTGCCAACACTGAGTGGTTGGATGGCAAGCATGTGGTCTTTGGCAAGGTGAAA
GAAAGCATGAGCATTGTAGAGGCCATGGAGCGCTTTGGGTCCAGGAATGGCAAGACCAACAAGAAGATCACCATTGCTGA
CTATGAACAACTC

Alignment

ORF - retro_ggor_2663 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 71.26 %
• Parental protein coverage: 99.4 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MVNPTVSFNIAVNGEPSGCVSFKLFADKFPKTAENFRALSTGEKGFDYKCSSFHRIIPGFMCQGGDFTRH
          MVNPT..F.IA.NGEP.G..S..LFAD.F.K.A.NF.ALST.EK...YK.S.FH.IIPG.MCQG.DFT.H
Retrocopy MVNPTMFFHIAINGEPLGHASLELFADMFSKSAKNFHALSTREKECGYKVSCFHKIIPGCMCQGVDFTCH

Parental  NGTGGKSIYGEKFDDENFILKHTGPGIL-SMANAGPNTNDSLFFF-ICTAKTEWLDGKHMVFGKVKDGMN
          NGT.GKS.Y.EKFDD.NF.LKHT.PGIL..MA.AGPNTN.S.FF...CTA.TEWLDGKH.VFGKVK..M.
Retrocopy NGTDGKSVYREKFDDDNFNLKHTHPGIL<AMAIAGPNTNHSQFFI<LCTANTEWLDGKHVVFGKVKESMS

Parental  IVEAMEHFGSGNGKTIKKITIADCTQL
          IVEAME.FGS.NGKT.KKITIAD..QL
Retrocopy IVEAMERFGSRNGKTNKKITIADYEQL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	0.00 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2663 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2663 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3966
Pan troglodytes	retro_ptro_2692
Callithrix jacchus	retro_cjac_1451

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Parental genes homology:

Parental genes homology involve 5 parental genes, and 37 retrocopies.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000026298	4 retrocopies	retro_ggor_138, retro_ggor_15, retro_ggor_165, retro_ggor_28,
Gorilla gorilla	ENSGGOG00000027442	1 retrocopy	retro_ggor_2663 ,
Macropus eugenii	ENSMEUG00000002016	20 retrocopies	retro_meug_1024, retro_meug_1055, retro_meug_1089, retro_meug_1133, retro_meug_1269, retro_meug_1391, retro_meug_1576, retro_meug_1746, retro_meug_1880, retro_meug_1975, retro_meug_2013, retro_meug_2037, retro_meug_260, retro_meug_297, retro_meug_301, retro_meug_437, retro_meug_478, retro_meug_510, retro_meug_713, retro_meug_73,
Monodelphis domestica	ENSMODG00000016089	9 retrocopies	retro_mdom_1373, retro_mdom_1524, retro_mdom_1856, retro_mdom_1884, retro_mdom_215, retro_mdom_272, retro_mdom_29, retro_mdom_730, retro_mdom_85,
Sarcophilus harrisii	ENSSHAG00000017062	3 retrocopies	retro_shar_164, retro_shar_383, retro_shar_750,