RetrogeneDB ID: retro_ggor_24

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 3:130850409..130851102(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000024500
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: GSTO1
• Ensembl ID: ENSGGOG00000005064
• Aliases: None
• Description: None

Sequence

>retro_ggor_24
ATGTTAGAGGAGTCAGCCAGGAGCCTGGGGAAGGGAAGCACGCCCCTGGGGCTGGTCCCAGAGGGGCTGATCTGCATCTG
CAGCATGAGGTTCTGCCCGTTTGCTGAGAGGACGCGTCTGGTTCTGAAGGCCGAGGGAATCAGGCATGAAGTCATCTATA
CCAACCTGAAAGATAAGCCTGAGTGGTTCTTTAAGAAAAATCCCTTTAGTTTGATGCCAGTTCTGGAAAACAGTCAGGGT
CAGCTGATCTACGAGTCTGCCATCACCTGTGAGTACCTGGATGAAGCATACTCAGGGAAGAAGCTGTTGCCGGATGACCC
CTATGAGAAAGCTTGCCAGAAGATGGTCTTTGAGTTGTTTTCTAAGGTGCCATCTTTGGTAGGAAGCTTCCTTAGAACCC
AAAATAAGGAAGACGGTGCTGGCCTGAAAGAAGCATTGTGTAAAGAATTTAGCAAGCTAGAGGAGGTTCTGATTAATAAG
AAGACAACCTTCTTTGGTGGCAATTCCGTCTCTATGATTGACTACCTCATCTGGCCCTCGTTTGAACGGCTGGAAGCAAT
GAAGTTAAATGAGTGTGTAGACCACACTCCAGAACTTAAACTGTGGATGGCAGCCATGAGGGAAGATCCCACAGTCTCAG
CCCTGCTCACTGTTGTGAAGGACTGGCAAGGTTTCACAGAGGTCTACTTACAG

Alignment

ORF - retro_ggor_24 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 85.28 %
• Parental protein coverage: 95.85 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MSGESARSLGKGSAPPGPVPEGSIRVYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFG
          M..ESARSLGKGS.P.G.VPEG.I...SMRFCPFAERTRLVLKA.GIRHEVI..NLK.KPEWFFKKNPF.
Retrocopy MLEESARSLGKGSTPLGLVPEGLICICSMRFCPFAERTRLVLKAEGIRHEVIYTNLKDKPEWFFKKNPFS

Parental  LVPVLENSQGQLIYESAITCEYLDEAYTGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYA
          L.PVLENSQGQLIYESAITCEYLDEAY.GKKLLPDDPYEKACQKM..ELFSKVPSLVGSF.R.QNKED.A
Retrocopy LMPVLENSQGQLIYESAITCEYLDEAYSGKKLLPDDPYEKACQKMVFELFSKVPSLVGSFLRTQNKEDGA

Parental  GLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDP
          GLKE...KEF.KLEEVL.NKKTTFFGGNS.SMIDYLIWP.FERLEAMKLNECVDHTP.LKLWMAAM.EDP
Retrocopy GLKEALCKEFSKLEEVLINKKTTFFGGNSVSMIDYLIWPSFERLEAMKLNECVDHTPELKLWMAAMREDP

Parental  TVSALLTSEKDWQGFLELYLQ
          TVSALLT..KDWQGF.E.YLQ
Retrocopy TVSALLTVVKDWQGFTEVYLQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	55.48 RPM
SRP007412_cerebellum	0.04 RPM	36.84 RPM
SRP007412_heart	0.03 RPM	50.53 RPM
SRP007412_kidney	0.04 RPM	79.45 RPM
SRP007412_liver	0.03 RPM	158.74 RPM
SRP007412_testis	0.00 RPM	18.23 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_24 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_24 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 8 parental genes, and 8 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000018474	1 retrocopy	retro_cjac_295,
Echinops telfairi	ENSETEG00000017967	1 retrocopy	retro_etel_1413,
Homo sapiens	ENSG00000148834	1 retrocopy	retro_hsap_2704,
Gorilla gorilla	ENSGGOG00000005064	1 retrocopy	retro_ggor_24 ,
Macaca mulatta	ENSMMUG00000015334	1 retrocopy	retro_mmul_142,
Nomascus leucogenys	ENSNLEG00000015358	1 retrocopy	retro_nleu_1577,
Pongo abelii	ENSPPYG00000002633	1 retrocopy	retro_pabe_2256,
Pan troglodytes	ENSPTRG00000002925	1 retrocopy	retro_ptro_1825,