RetrogeneDB ID: retro_dnov_1961

Retrocopy location

• Organism: Armadillo (Dasypus novemcinctus)
• Coordinates: scaffold_3895:116556..117229(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: AIDA
• Ensembl ID: ENSDNOG00000008380
• Aliases: None
• Description: axin interactor, dorsalization associated [Source:HGNC Symbol;Acc:25761]

Sequence

>retro_dnov_1961
CTTTACAGTCCAGAGTCCCAAGAAGAATTTAAACTGGGGGATTTGAAGAAATTAGAACTAATCCTAAAGAATATTTTTAC
ATGTAATAAAGAGTTCCCATTTGACGTTCAGCCTGTCCCAGTTAAGAAGAATTTTAGCACCTGGTGTAGAATAGAATCTG
GAATTTGAAGGGGATAAAGAGGAAGGTGGTGTGGAGCTGGATATCCTGATTCCTCTCCCGCAAGTGTTCTGGTACTTTAT
CACCAAGGTTATGGTCAGAACAGGAATGGTGTTACTACATCAGAACTGAGGAGATGGGTCTGAAAGATGCTGGGCCGTGC
ATCGATCCCTATGTTACAGTTAATGTAAAGGATGTGAAGGTCATAGACTTAACTCTTGTGCAAGATACTCCTGTGGCTTC
AAGAGAAGAAGATATATATGTTTATTTTTAATGTGGACCCTGGGATCCAGAAGCATGTTGAAAAGTCACCAAAGGTGCAG
CTCTCCTCTTTGAATTCAAACGGTACAAGCCTAAGAAAAGATTTACCAGCACCAAGTGTTTTGCTTTCATGGAAATGGAT
GAAATTAAACCTGGACCAACAGAACTATACAAGAAACCCACTGACTTTAAAAGAAAGAAATTGTAGTTATTGTCCAACTT
TATCTTCATCTACATCAAACTTTGCACAAGGAA

Alignment

ORF - retro_dnov_1961 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 73.31 %
• Parental protein coverage: 75.16 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 6

Retrocopy - Parental Gene Alignment:

Parental  LQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVP-LRRILAPGEEENLEFEEDEEEGGA-GAGS
          L.S..SQEEFKL.DLKKLE.ILKNI.T.NKEFPFDVQPVP.LRRILAPG.E.NLEFE.D.EEGG..GAG.
Retrocopy LYSPESQEEFKLGDLKKLELILKNIFTCNKEFPFDVQPVP>LRRILAPGVE*NLEFEGDKEEGGV<GAGY

Parental  PDSFPARV-PGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRK
          PDS.PA.V..GTL.PRL.SE.......IR.E..GLKDAG.CIDPY.TV.VKD...IDLT.VQDTPVASR.
Retrocopy PDSSPASV<SGTLSPRLWSEQEWCYY-IRTEEMGLKDAGPCIDPYVTVNVKDVKVIDLTLVQDTPVASRE

Parental  EDTYVH-FNVDIELQKHVE-KLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDELKPGPIVIELYKKPTD
          ED.YV..FNVD...QKHVE.K.TKGAA..FEFK.YKPKKRFTSTKCFAFMEMDE.KPGP...ELYKKPTD
Retrocopy EDIYVY>FNVDPGIQKHVE<KVTKGAALLFEFKRYKPKKRFTSTKCFAFMEMDEIKPGP--TELYKKPTD

Parental  FKRKKLQLLT-KKPLYLHLHQTLHKE
          FKRKKL.LL.....L.LH..QTLHKE
Retrocopy FKRKKL*LLS<QLYLHLH--QTLHKE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012922_ascending_colon	0.00 RPM	32.48 RPM
SRP012922_cerebellum	0.00 RPM	26.39 RPM
SRP012922_heart	0.00 RPM	12.53 RPM
SRP012922_kidney	0.00 RPM	14.78 RPM
SRP012922_liver	0.00 RPM	14.24 RPM
SRP012922_lung	0.00 RPM	32.07 RPM
SRP012922_quadricep_muscle	0.00 RPM	21.64 RPM
SRP012922_spleen	0.00 RPM	58.26 RPM

ChIP-Seq

Dasypus novemcinctus was not studied using ChIP-Seq data.

EST

Dasypus novemcinctus was not studied using EST data.

TSS

Dasypus novemcinctus was not studied using FANTOM5 data.

Lab

retro_dnov_1961 was not experimentally validated.

Homology

Retrocopy orthology:

Dasypus novemcinctus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 13 parental genes, and 31 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000007593	2 retrocopies	retro_btau_1163, retro_btau_573,
Choloepus hoffmanni	ENSCHOG00000010095	2 retrocopies	retro_chof_1919, retro_chof_97,
Dasypus novemcinctus	ENSDNOG00000008380	5 retrocopies	retro_dnov_1765, retro_dnov_1909, retro_dnov_1961 , retro_dnov_2172, retro_dnov_2280,
Homo sapiens	ENSG00000186063	4 retrocopies	retro_hsap_1901, retro_hsap_2076, retro_hsap_2998, retro_hsap_410,
Gorilla gorilla	ENSGGOG00000015289	3 retrocopies	retro_ggor_1394, retro_ggor_1627, retro_ggor_2077,
Macaca mulatta	ENSMMUG00000015025	1 retrocopy	retro_mmul_1918,
Monodelphis domestica	ENSMODG00000004774	3 retrocopies	retro_mdom_1417, retro_mdom_1418, retro_mdom_1448,
Nomascus leucogenys	ENSNLEG00000013583	1 retrocopy	retro_nleu_748,
Oryctolagus cuniculus	ENSOCUG00000017030	1 retrocopy	retro_ocun_688,
Pongo abelii	ENSPPYG00000000196	2 retrocopies	retro_pabe_2015, retro_pabe_2485,
Pan troglodytes	ENSPTRG00000002010	3 retrocopies	retro_ptro_1254, retro_ptro_1528, retro_ptro_2027,
Tarsius syrichta	ENSTSYG00000005745	3 retrocopies	retro_tsyr_101, retro_tsyr_1795, retro_tsyr_514,
Tursiops truncatus	ENSTTRG00000016594	1 retrocopy	retro_ttru_1084,