RetrogeneDB ID: retro_chof_577

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_123187:3214..3867(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: NSMCE4A
• Ensembl ID: ENSCHOG00000003695
• Aliases: None
• Description: non-SMC element 4 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:25935]

Sequence

>retro_chof_577
TTTAATCAAGTAGCGTTTGTGACTTTCTATTTATATTTGTGGGTCTAAATTGGATGGAAGATGAACATGATGAGCTGAGT
GATTGTGATGATATTATAGCACTTTCCTTTTGGGAGACAGTACAAAAGGAAGCAACATCCTGGATATTGCAAGCCGAAAC
GTTCCATTTCATTTTTGGTTCTTTCAAGCAAGAGCCTTCTGCACGAAAGTCACGTCTTGAACATCAGAAAAAAGCTCACA
AAATGGAAGAAAATGGGGATATGCCGACAAAATTGAAGAAGTTGGACCTGAGTAGTAATCAAGAAGCCACAGAAAAAGAA
GTAGAAAGAATCCTAGGCTTGTTGCAAACCTACTTTCGAAAGTATCCTGATAGTCCTGTGTCCTATTTTGAATTTGTGAT
TGATCCAAACTCTTTTTCTCGCACTGTGGAGAATATATTTTATGTTTCTTTCATTATAAGGGATGGTTTTGCAAGAATAA
GGCTTGACCAAGACAGGTTGCCAGTATTAGAGCCAATTAATATTGACCAAATGGGAGAGGGAAACAATAGCATTTCCAAC
GGCAGGAAACAAGGAGTTATATCTTTGAGTTTACAAGACTGGAAAAATATTGTGGCAACTTTTGAGATTTCAGAGGCTAT
GATTACAAACTCA

Alignment

ORF - retro_chof_577 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 50.9 %
• Parental protein coverage: 72.76 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  FDMLRYVETLLTLTV-VNPLEDEELFRDEDSSDYEVLAYDSWKISRRTAENTCNKTHTFHFLLGSIQGEA
          F.....V...L.L.V..N..EDE....DE.S......A...W......A........TFHF..GS...E.
Retrocopy FNQVAFVTFYLYLWV<LNWMEDEH---DELSDCDDIIALSFWETVQKEATSWILQAETFHFIFGSFKQEP

Parental  PVPKPRVDRPKKVRVIEEQRAMPAQLKRME-ESQQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDP
          ...K.R....KK....EE...MP..LK.....S.QEATEKEVERILGLLQTYFR..PD.P.S.F.FV.DP
Retrocopy SARKSRLEHQKKAHKMEENGDMPTKLKKLDLSSNQEATEKEVERILGLLQTYFRKYPDSPVSYFEFVIDP

Parental  HSFPRTVENIFHVSFII-DGFARIRLDQDRLPIIEPVNINEESEGIDQNTQTRNQGILALSYRDWEEIVK
          .SF.RTVENIF.VSFII.DGFARIRLDQDRLP..EP.NI....EG.......R.QG...LS..DW..IV.
Retrocopy NSFSRTVENIFYVSFIIRDGFARIRLDQDRLPVLEPINIDQMGEGNNSISNGRKQGVISLSLQDWKNIVA

Parental  TFEISEPVIASS
          TFEISE..I..S
Retrocopy TFEISEAMITNS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_577 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 22 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000010897	1 retrocopy	retro_amel_419,
Bos taurus	ENSBTAG00000019166	1 retrocopy	retro_btau_1387,
Canis familiaris	ENSCAFG00000012419	2 retrocopies	retro_cfam_1427, retro_cfam_379,
Choloepus hoffmanni	ENSCHOG00000003695	1 retrocopy	retro_chof_577 ,
Dipodomys ordii	ENSDORG00000003880	1 retrocopy	retro_dord_677,
Equus caballus	ENSECAG00000016651	2 retrocopies	retro_ecab_109, retro_ecab_465,
Erinaceus europaeus	ENSEEUG00000014906	1 retrocopy	retro_eeur_124,
Felis catus	ENSFCAG00000003647	1 retrocopy	retro_fcat_994,
Homo sapiens	ENSG00000107672	1 retrocopy	retro_hsap_43,
Loxodonta africana	ENSLAFG00000004214	1 retrocopy	retro_lafr_1051,
Macaca mulatta	ENSMMUG00000012044	1 retrocopy	retro_mmul_716,
Mustela putorius furo	ENSMPUG00000002960	1 retrocopy	retro_mputfur_396,
Nomascus leucogenys	ENSNLEG00000016919	1 retrocopy	retro_nleu_2073,
Otolemur garnettii	ENSOGAG00000010026	1 retrocopy	retro_ogar_280,
Pongo abelii	ENSPPYG00000002712	1 retrocopy	retro_pabe_878,
Pteropus vampyrus	ENSPVAG00000017186	2 retrocopies	retro_pvam_1163, retro_pvam_795,
Rattus norvegicus	ENSRNOG00000020452	1 retrocopy	retro_rnor_2515,
Ictidomys tridecemlineatus	ENSSTOG00000011112	1 retrocopy	retro_itri_36,
Vicugna pacos	ENSVPAG00000006534	1 retrocopy	retro_vpac_260,