RetrogeneDB ID: retro_ggor_761

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 11:128859187..128859815(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000016227
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: BAK1
• Ensembl ID: ENSGGOG00000022462
• Aliases: None
• Description: None

Sequence

>retro_ggor_761
ATGGCATCGGGGCAAGGCCCAGGGCCTCCCAGGCAGGAGTGCGGAAAGCCTGCCCTGCGCTCTGCTTCTGAGGAGCAGGT
AGCCCAGGACACGGAGGGGTTTTCCGCAGCTACGTTTTTTACCACCATCAGCAGGAACAGGAGGCTGAAGGGGCGGCCGC
CCCTGCCAACCCAGAGATGGCACCCTGCGCCTCCAACCTAGAAGCACCATGGGGCAGGTGGGACGGCAGCTCGCCATCAC
CAGGACGACATCAACCGGCACTATGACTTCGGAGTTCCAGACCATGCTGCAGCGTCTGCAGCCCAGGGCAGAGAACGCCT
ACGAGTACTTCACCAAGATCGCCTCCAGCCTGTTTGAGAGTGGCATCAACCGGGGCCGTGTGGTGGCTCTCCTGGGCTTC
GGCTACCGTCTGGTCTTACACGTCTACCAGCACAGCCTGACTGGCTTCCTGGGCCTGGTGACCCGCTTCGTGGTCTTCAT
GCTGCAACACGGCATTGCCCGGTGGATCTCGCAGAGGGGCGGCTGGGTGGCAGCCCCGGACTTGGGCAATAGTCCCATCC
TGAACGTGCTGGTGGTTGTGGGTGGGGTTCTGCTGGGCCAGTTTGTGGTAAGAAGATTCTTCAAATCA

Alignment

ORF - retro_ggor_761 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 85.58 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  MASGQGPGPPRQECGEPALPSASEEQVAQDTEE-VFRSYVFYRHQQEQEAEGAAAPADPEMV-TLPLQPS
          MASGQGPGPPRQECG.PAL.SASEEQVAQDTE..VFRSYVFY.HQQEQEAEGAAAPA.PEM..TL.LQP.
Retrocopy MASGQGPGPPRQECGKPALRSASEEQVAQDTEG<VFRSYVFYHHQQEQEAEGAAAPANPEMA<TLRLQPR

Parental  STMGQVGRQLAIIG-DDINRRYD-SEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGY
          STMGQVGRQLAI...DDINR.YD.SEFQTMLQ.LQP.AENAYEYFTKIA.SLFESGIN.GRVVALLGFGY
Retrocopy STMGQVGRQLAITR<DDINRHYD>SEFQTMLQRLQPRAENAYEYFTKIASSLFESGINRGRVVALLGFGY

Parental  RLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWVAALNLGNGPILNVLVVLGVVLLGQFVVR
          RL.LHVYQH.LTGFLG.VTRFVV.FML.H.IARWI.QRGGWVAA..LGN.PILNVLVV.G.VLLGQFVVR
Retrocopy RLVLHVYQHSLTGFLGLVTRFVV-FMLQHGIARWISQRGGWVAAPDLGNSPILNVLVVVGGVLLGQFVVR

Parental  RFFKS
          RFFKS
Retrocopy RFFKS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	7.19 RPM
SRP007412_cerebellum	0.00 RPM	8.79 RPM
SRP007412_heart	0.06 RPM	13.66 RPM
SRP007412_kidney	0.00 RPM	17.13 RPM
SRP007412_liver	0.00 RPM	9.76 RPM
SRP007412_testis	0.10 RPM	6.73 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_761 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_761 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_942
Pan troglodytes	retro_ptro_652
Macaca mulatta	retro_mmul_1130

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Parental genes homology:

Parental genes homology involve 7 parental genes, and 9 retrocopies.

Species	Parental gene accession	Retrocopies number
Felis catus	ENSFCAG00000013657	1 retrocopy	retro_fcat_202,
Homo sapiens	ENSG00000030110	2 retrocopies	retro_hsap_2468, retro_hsap_942,
Gorilla gorilla	ENSGGOG00000022462	1 retrocopy	retro_ggor_761 ,
Macaca mulatta	ENSMMUG00000009104	1 retrocopy	retro_mmul_1130,
Nomascus leucogenys	ENSNLEG00000008351	1 retrocopy	retro_nleu_296,
Ochotona princeps	ENSOPRG00000001127	2 retrocopies	retro_opri_105, retro_opri_938,
Pan troglodytes	ENSPTRG00000018053	1 retrocopy	retro_ptro_652,