RetrogeneDB ID: retro_ggor_2605

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 7:63431809..63432351(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: GNA14
• Ensembl ID: ENSGGOG00000013561
• Aliases: None
• Description: None

Sequence

>retro_ggor_2605
TGTTGCCTGAGCGATAAGGTGAAGGAATCCAAGCGGATCAACGCCGAGATCCAGAAGCAGCTGCGGGGGACAAGCGCGAC
GCCCGGCGCCAGCTCAAGCTGCTGCTGCTCCTCACGGGCGAGAGCGGGAAGAGCACGTTCATCAAGCAGATGCGCATCAT
CCATGGCGCCGGCTACTCGGAGGAGGACAAGCGCGGCTTCACCAAGCTCGTCTACCAGAACATCTTCACCGCCATGCAGG
CCATGATCCGGGCCATGGAGACGCTGAAGATCCTCTACAAGTAGGAGCAGAACAAGGCCAATGCGCTCCAGATCCGAGAG
GTGGACGTGGAGAAGGTGACCACCTTCGAGCATCCGTACGTCAGCGCCATCAAGACCCTGTGGGACGACCCCGGCATCCA
CGAGTGCTACGACCGCAGTCGCGAGTACCAGCTCTCGGACTCGGCCAAGTACTGCTTTACCGACGTAGACTGCATCGCCA
CCTCGAGCTACCTGCCCACCCAGCAGGACGTGCTGCGGGTCCGCGTGCCCACCACCGGCATC

Alignment

ORF - retro_ggor_2605 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 75.27 %
• Parental protein coverage: 50.99 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  CCLSAEEKESQRISAEIERQLRR-DKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTK
          CCLS...KES.RI.AEI..QLR..DK.DARR.LKLLLL.TGESGKSTFIKQMRIIHG.GYS.ED..GFTK
Retrocopy CCLSDKVKESKRINAEIQKQLRG<DKRDARRQLKLLLLLTGESGKSTFIKQMRIIHGAGYSEEDKRGFTK

Parental  LVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSMLSREQVEAIKQLWQDPGIQECYDR
          LVYQNIFTAMQAMIRAM.TL.I.Y..EQNK.NA..IREV.V.KV.......V.AIK.LW.DPGI.ECYDR
Retrocopy LVYQNIFTAMQAMIRAMETLKILYK*EQNKANALQIREVDVEKVTTFEHPYVSAIKTLWDDPGIHECYDR

Parental  RREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGI
          .REYQLSDSAKY..TD.D.IAT.S..PTQQDVLRVRVPTTGI
Retrocopy SREYQLSDSAKYCFTDVDCIATSSYLPTQQDVLRVRVPTTGI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.10 RPM	1.58 RPM
SRP007412_cerebellum	0.00 RPM	0.47 RPM
SRP007412_heart	0.00 RPM	0.44 RPM
SRP007412_kidney	0.00 RPM	9.24 RPM
SRP007412_liver	0.00 RPM	9.87 RPM
SRP007412_testis	0.00 RPM	15.23 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2605 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2605 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 3 parental genes, and 5 retrocopies.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000013561	1 retrocopy	retro_ggor_2605 ,
Gorilla gorilla	ENSGGOG00000014995	3 retrocopies	retro_ggor_1760, retro_ggor_2603, retro_ggor_2604,
Pan troglodytes	ENSPTRG00000021042	1 retrocopy	retro_ptro_1694,