RetrogeneDB ID: retro_ggor_1804

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 2b:95014372..95014990(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000024971
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: ACER2
• Ensembl ID: ENSGGOG00000003851
• Aliases: None
• Description: None

Sequence

>retro_ggor_1804
CTCTTGGTTGTAGCGGGAATTGGATCCGTCTACTTCCATGCAACCCTTAGTTTCCTGGGTCAGATGCTTGATGAACTTGC
AGTCCTTTGGGTTCTGATGTGTGCTTTGGTCATGTGGTTCCCCAGAAGGTATCTACCAAAGATCTTTCGGAATGACCAGG
GTAGGTTCAAGGTGGTGGTCTGTGTCCTGTCTGCAGTTACCACGTGCCTGGCATTTGTCAAGCCTGCCATCAACAACATC
TCTCTGATGACCCTGGGAGTTCCTTGCGCTGCACTGCTCATCACAGAGCTAAAGAGGTGTGACAACATGCGTGTGTTTAA
GCTGGGCCTCTTCTCGGGCCTCTGGTGGACCCTGGCCCTGTTCTGCTGGATCAGTGACCGAGCTTTCTGTGAGCTGCTGT
CATCCTTCAACTTCCCCTACCTGCACTGCATGTGGCACATCCTCATCTGCCTTGCTGCCTACCTGGGCTGTGTATGCTTT
GCCTACTTTGATGCTGCCTCAGAGATTCCTGAGCAAGGCCCTGTCATCAAATTCTGGCCCAGTGAGAAATGGGCCTTCAT
TGGTGTCCCCTATGTGTCCCTCCTGTGTGCCAACAAGAAATCATCAGTCAAGACCACG

Alignment

ORF - retro_ggor_1804 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 94.66 %
• Parental protein coverage: 74.1 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  LSLILGIGSVYFHATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRNDRGRFKVVVSVLSAVTTCL
          L....GIGSVYFHATLSFLGQMLDELAVLWVLMCAL.MWFPRRYLPKIFRND.GRFKVVV.VLSAVTTCL
Retrocopy LLVVAGIGSVYFHATLSFLGQMLDELAVLWVLMCALVMWFPRRYLPKIFRNDQGRFKVVVCVLSAVTTCL

Parental  AFVKPAINNISLMTLGVPCTALLIAELKRCDNMRVFKLGLFSGLWWTLALFCWISDRAFCELLSSFNFPY
          AFVKPAINNISLMTLGVPC.ALLI.ELKRCDNMRVFKLGLFSGLWWTLALFCWISDRAFCELLSSFNFPY
Retrocopy AFVKPAINNISLMTLGVPCAALLITELKRCDNMRVFKLGLFSGLWWTLALFCWISDRAFCELLSSFNFPY

Parental  LHCMWHILICLAAYLGCVCFAYFDAASEIPEQGPVIKFWPNEKWAFIGVPYVSLLCANKKSSVKIT
          LHCMWHILICLAAYLGCVCFAYFDAASEIPEQGPVIKFWP.EKWAFIGVPYVSLLCANKKSSVK.T
Retrocopy LHCMWHILICLAAYLGCVCFAYFDAASEIPEQGPVIKFWPSEKWAFIGVPYVSLLCANKKSSVKTT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	1.34 RPM
SRP007412_cerebellum	0.00 RPM	1.81 RPM
SRP007412_heart	0.00 RPM	0.72 RPM
SRP007412_kidney	0.00 RPM	1.02 RPM
SRP007412_liver	0.03 RPM	0.55 RPM
SRP007412_testis	0.10 RPM	2.69 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1804 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1804 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2378
Pongo abelii	retro_pabe_2147

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 4 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000177076	1 retrocopy	retro_hsap_2378,
Gorilla gorilla	ENSGGOG00000003851	1 retrocopy	retro_ggor_1804 ,
Myotis lucifugus	ENSMLUG00000007595	1 retrocopy	retro_mluc_727,
Pongo abelii	ENSPPYG00000019192	1 retrocopy	retro_pabe_2147,