RetrogeneDB ID: retro_mputfur_92

Retrocopy location

• Organism: Ferret (Mustela putorius furo)
• Coordinates: GL896981.1:8061209..8063807(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMPUG00000018953
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: SMEK2
• Ensembl ID: ENSMPUG00000002435
• Aliases: None
• Description: SMEK homolog 2, suppressor of mek1 (Dictyostelium) [Source:HGNC Symbol;Acc:29267]

Sequence

>retro_mputfur_92
ATGGAGAGAGGGAAACCTAAGATGGAAGTGAGAGGAAGTGGGACTCGAGGGAACTCTGCGGACCTCAGGAACCACCAGCG
TCCACCTGAACGCTACTTCTCTGCCATCTTCCACCGTAATTTTCCCCTCCCGCCACCTGAGCAATGGTCGCTGCCACAAC
AGCGACAACTACAGTCAACTCCAGGCACATGCGACCCAGCGGCCCCCCACACCGAGACCAACACTGGGGACGGGAAGCCA
GCGGTCGCCATTGCCGACACACGGTATCTTGTAAAAGTCTACTCACTGAATGAGGACCAACAATGGGATGATCTCGGCAC
CGGGCACGTCTCCTCTACTTATGTGAAGCGCCTCCAGGGTGTGTCCCTGCTCGTTAGGTCGGATTCCCAGGCCGCACTAA
TCTTGGAATCAAAGATAAATTCAAATACCCCCTATCAGAAACAACAGGAAACCCTGATTATTTGGTCTGAAGGAGAGAAC
CATGGTGTGGCATTAAGTTTCCAGGACACTGAGGGTTGCCATAAGATCTGGGAAGAAATTTGCCACATTCAGGGAAAAGA
CCCATCCATCAAAATCACACAAGATCTCTTGGAGGAATCCAAAGAAGAACAACTGCATGACGTCCTGGAAACCAATAATG
TGTTTGACCTGCCTAACTGTGAACTCTGTAAACTTGAAGAGATTGCTGACTTCATTACCGCCGTTCTCGCTTCACCGATC
CGTAAGGAGAGACTGGCTCTGATCTTAGAAAATGACGACTATATTAAAAATTTGCTGCAGCTGTTCCACACTTGTGAGGA
CCTAGGGAACACTGCAGGCTTACATCATTTGCATACAATTATTAAAGGCATCTTATTCCTTAACAAGACAGCTCTGTTTG
AGATCATGTTTTCTGCTGAGTGTATCATGGATGTGGTGGGATGTCTTGAATATGACCCTGCTTTGGCTCAGCCAAAAAGG
CATAGGGAATTCTTGACCCAACATGCAAGGCTCAAGGAAGTTGTACCAATAACAAACGGTGAACTTAGGCAAAAAATACA
TCAGACATATAAGATACAGTACATCTATGACATACTTTTGCCAGCACCATCCATGTATGAAGAGAACTTTCTTTCGAGTC
TTACAACTTTTATTTTCCTCAACAAGGTTGAGATAGTCAGCATGTTGCAGGACGAAAACTTTTTGTCTGAAGTCTTTGCA
CAGTTAAAGAATGCGGCAATAGATGATGATAGACGGCGTGAATTGCTACTTTTCTTCAAGGAATTCTGTGCATTTTCTCA
GACATTACAGCCTCCAAAGAAGGATGCTCTGTTCAAAACACTGACAGAATTGGGAATTCTTCCTGTTCTTAAAATCGTAA
TGAGCATGGAGAATTTGCAAATAAGGTCAGCTGCTACTGATATATTTACTTATCTCGTAGAGTATAGTCCATCCATGATT
CGAGAATTTATCATGGAAGAAGCTCAGGAGAGTGAAGATGGTAACCTTTTCATTAACTTAGTCATTGAGCAAATGATCTG
CGATACTGATCCTGAGCTAGGAGGTGCTGTTCATTTAATGGGACTTCTTCGTACTCTTCTTGATCCAGAAAACATGCATG
CAACATCTACTAAATGTGAAAGAAGTGAATTCCTAAATTTTTTCTACAAGCATTGTATACACAACTTCATAGCACCACTT
GTTGCCACCACTTCAGAAGATATATGTGAAGGGGATAGTGAAGTTGGGTCTGACGAAAACAACACACATTGCCTCAATAA
TTATCAAACAGCACAGCTGCTTTCTTTAATTTTAGAGCTGCTCACATTTTGTGTGCAACATCACACATACTACATAAAAA
ATTATATTTTGAGCAAAGACTTGCTAAGAAGAGTCTTGATCTTGATAAATTCAAAGCACACTTTCCTGGTCTTGAGTTCG
CTCCGCTTTATGAGAAGGATGATTGGCCTTAAAGATGAACTTTATAATTGTTACATCATCAAGGGAAATCTTTTTGAACC
AGTTGTCAAAGCTCTTCTGGGTAATGGAACTCGGTACAATATGTTGAATTCAGCTGCTATTGAGCTGTTTGAATACATAA
GAGCGGAAAATATCAAATCTCTTATTACACATATAGTTGAAAAGTTTTATAAGGCACTTGAATCGATTGAATATGTCCAG
ACATTCAAAGGATTGAAGATTAAATATGAACAAGAAAAAGACCGGCAGAATCAAATACGGAAGAATTTACATTCTATCTT
GCATAGTAAAATACTTCGCAGGAGTACCAGAGTCATGGACAAGAAGGAAGAAAAGTGTCTTAAAGGAAATTCAGAGGAAG
GAGAAGCAACTATGCCACCACTGGAAGACAATTTTCAAGATCGTTTCAAATTTATGGAGACTAAAAAACCAAAGGAAAAT
GAAGACAAGGTAGCTCCTCCTAAAAGATCATCTTCAGGGGGCTACAAATACACCATATCCCATTCTGCTGCTGCTGCTAA
TGGAACACGTAGCCTGCAGGGAAGCAGCACTGTTGGCTTAATGAATCCTCCCGATGATGATGAAAAAGATAAGGAAGATG
AAACATCTCCCAGGAAGAGACCACATCTTAGCCTGTAA

Alignment

ORF - retro_mputfur_92 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 70.9 %
• Parental protein coverage: 85.8 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLI
          ..DTR..VKVY.LNED.QWDD.GTGHVSSTYV..L.G.SLLVR..S...L.LESKIN.NT.YQKQQ.TLI
Retrocopy IADTRYLVKVYSLNEDQQWDDLGTGHVSSTYVKRLQGVSLLVRSDSQAALILESKINSNTPYQKQQETLI

Parental  VWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELS
          .WSE.EN...ALSFQ...GC..IWE.IC..QGKDPS...TQDL..ES.EE......ET....DLP.CEL.
Retrocopy IWSEGENHGVALSFQDTEGCHKIWEEICHIQGKDPSIKITQDLLEESKEEQLHDVLETNNVFDLPNCELC

Parental  KLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLF
          KLEEIAD..T.VL.SPIR.E.LAL.LEN..YIK.LLQLF..CE.L.NT.GLHHL..II.GILFLNK..LF
Retrocopy KLEEIADFITAVLASPIRKERLALILENDDYIKNLLQLFHTCEDLGNTAGLHHLHTIIKGILFLNKTALF

Parental  EVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTP
          E.MFS.ECIMDVVGCLEYDPALAQPKRHREFLT..A..KEV.PIT..ELRQKIHQTY..QYI.DI.LP.P
Retrocopy EIMFSAECIMDVVGCLEYDPALAQPKRHREFLTQHARLKEVVPITNGELRQKIHQTYKIQYIYDILLPAP

Parental  SVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQ
          S..EENFLS.LT.FIF.NKVEIVSMLQ.DE.FLSEVFAQL...A.DDD.RREL..FFKEFCAFSQTLQP.
Retrocopy SMYEENFLSSLTTFIFLNKVEIVSMLQ-DENFLSEVFAQLKNAAIDDDRRRELLLFFKEFCAFSQTLQPP

Parental  NRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI
          ..DA.FKTL..LGILP.L.IVM.M..LQ.RSAATDIF.YLVE.SPSM.REF.M.EAQ.S.D..L.IN.VI
Retrocopy KKDALFKTLTELGILPVLKIVMSMENLQIRSAATDIFTYLVEYSPSMIREFIMEEAQESEDGNLFINLVI

Parental  EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKD
          EQMICDTDPELGGAV.LMGLLRTL.DPENM.AT..K.E.SEFLNFFY.HC.H...APL...TSED.CE.D
Retrocopy EQMICDTDPELGGAVHLMGLLRTLLDPENMHATSTKCERSEFLNFFYKHCIHNFIAPLVATTSEDICEGD

Parental  NIVGSNKNSTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALR
          ..VGS..N.T.C..NYQTAQLL.LILELLTFCV.HHTY.IKNYI..KDLLRRVL.L.NSKHTFL.L..LR
Retrocopy SEVGSDENNTHCLNNYQTAQLLSLILELLTFCVQHHTYYIKNYILSKDLLRRVLILINSKHTFLVLSSLR

Parental  FMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKA
          FMRR.IGLKDE.YN.YI.KGNLFEPV..ALL.NGTRYN.LNSA.IELFE.IR.E.IKSL..HIVE.FYKA
Retrocopy FMRRMIGLKDELYNCYIIKGNLFEPVVKALLGNGTRYNMLNSAAIELFEYIRAENIKSLITHIVEKFYKA

Parental  LESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPV
          LESIEYVQTFKGLK.KYEQEKDRQNQ......SIL.S...RR........EE........EEG.A...P.
Retrocopy LESIEYVQTFKGLKIKYEQEKDRQNQIRKNLHSILHSKILRRSTRVMDKKEEKCL-KGNSEEGEATMPPL

Parental  E
          E
Retrocopy E

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Mustela putorius furo was not studied using RNA-Seq expression data.

ChIP-Seq

Mustela putorius furo was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mputfur_92 retrocopy.

TSS

Mustela putorius furo was not studied using FANTOM5 data.

Lab

retro_mputfur_92 was not experimentally validated.

Homology

Retrocopy orthology:

Mustela putorius furo does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 18 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000003843	1 retrocopy	retro_amel_48,
Bos taurus	ENSBTAG00000000545	1 retrocopy	retro_btau_232,
Canis familiaris	ENSCAFG00000002860	1 retrocopy	retro_cfam_226,
Equus caballus	ENSECAG00000013819	1 retrocopy	retro_ecab_23,
Echinops telfairi	ENSETEG00000002420	1 retrocopy	retro_etel_1699,
Felis catus	ENSFCAG00000026457	1 retrocopy	retro_fcat_13,
Homo sapiens	ENSG00000138041	1 retrocopy	retro_hsap_4799,
Loxodonta africana	ENSLAFG00000017825	1 retrocopy	retro_lafr_791,
Myotis lucifugus	ENSMLUG00000003875	1 retrocopy	retro_mluc_994,
Macaca mulatta	ENSMMUG00000007001	1 retrocopy	retro_mmul_238,
Mustela putorius furo	ENSMPUG00000002435	1 retrocopy	retro_mputfur_92 ,
Nomascus leucogenys	ENSNLEG00000009338	1 retrocopy	retro_nleu_1112,
Oryctolagus cuniculus	ENSOCUG00000006880	1 retrocopy	retro_ocun_9,
Otolemur garnettii	ENSOGAG00000009837	1 retrocopy	retro_ogar_140,
Pan troglodytes	ENSPTRG00000011933	1 retrocopy	retro_ptro_3191,
Sus scrofa	ENSSSCG00000008398	1 retrocopy	retro_sscr_1187,
Ictidomys tridecemlineatus	ENSSTOG00000006276	1 retrocopy	retro_itri_63,
Tursiops truncatus	ENSTTRG00000000027	1 retrocopy	retro_ttru_1397,