RetrogeneDB ID: retro_ggor_489

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:224138041..224138317(-)
• Located in intron of: ENSGGOG00000007722

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: FABP7
• Ensembl ID: ENSGGOG00000025475
• Aliases: None
• Description: None

Sequence

>retro_ggor_489
TCAAGAAGGAGACAAAAGGTGGTGATCAGGATTCAAAGTATGTTCAAGAACACAGAGGTTAGTTTCCATATGGGAGAAGA
GTTTGATGAAACCACTACAGATGACAGAAACTGCAAGTTTGTTGTTAGTCTGGATAGAGACAAACTCATTCACATACAGA
AATGGGATGACAAAGAAACATATTTTATAAGAGAAATTAAGTATGGTGAAATGGTTATGACTTACTTTTGGTGTTTTGGT
GATGATGTGGTTGCCGTTCACCACTATAAGAAGGCA

Alignment

ORF - retro_ggor_489 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 72.83 %
• Parental protein coverage: 67.42 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  SQEGDKVVIRTLSTFKNTEISFHLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGK
          S....KVVIR..S.FKNTE.SFH.GEEFDETT.DDRNCK.VVSLD.DKL.HIQKWD.KET.F.REIK.G.
Retrocopy SRRRQKVVIRIQSMFKNTEVSFHMGEEFDETTTDDRNCKFVVSLDRDKLIHIQKWDDKETYFIREIKYGE

Parental  MVMTL--TFG-DVVAVRHYEKA
          MVMT....FG.DVVAV.HY.KA
Retrocopy MVMTYFWCFGDDVVAVHHYKKA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.14 RPM	28.68 RPM
SRP007412_cerebellum	0.28 RPM	73.12 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.04 RPM
SRP007412_liver	0.00 RPM	0.03 RPM
SRP007412_testis	0.00 RPM	0.00 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_489 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_489 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_536
Pan troglodytes	retro_ptro_402
Pongo abelii	retro_pabe_213
Macaca mulatta	retro_mmul_458

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Parental genes homology:

Parental genes homology involve 13 parental genes, and 20 retrocopies.

Species	Parental gene accession	Retrocopies number
Cavia porcellus	ENSCPOG00000014056	1 retrocopy	retro_cpor_34,
Homo sapiens	ENSG00000164434	1 retrocopy	retro_hsap_536,
Gorilla gorilla	ENSGGOG00000005964	8 retrocopies	retro_ggor_1005, retro_ggor_1163, retro_ggor_2079, retro_ggor_2276, retro_ggor_2284, retro_ggor_2563, retro_ggor_2931, retro_ggor_940,
Gorilla gorilla	ENSGGOG00000014432	1 retrocopy	retro_ggor_990,
Gorilla gorilla	ENSGGOG00000016835	1 retrocopy	retro_ggor_2488,
Gorilla gorilla	ENSGGOG00000025475	1 retrocopy	retro_ggor_489 ,
Macaca mulatta	ENSMMUG00000021907	1 retrocopy	retro_mmul_458,
Oryctolagus cuniculus	ENSOCUG00000001497	1 retrocopy	retro_ocun_1874,
Otolemur garnettii	ENSOGAG00000031110	1 retrocopy	retro_ogar_2821,
Ochotona princeps	ENSOPRG00000000992	1 retrocopy	retro_opri_840,
Pongo abelii	ENSPPYG00000016979	1 retrocopy	retro_pabe_213,
Pan troglodytes	ENSPTRG00000018564	1 retrocopy	retro_ptro_402,
Sarcophilus harrisii	ENSSHAG00000003313	1 retrocopy	retro_shar_521,