RetrogeneDB ID: retro_mdom_555

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 1:286966712..286967227(-)
• Located in intron of: ENSMODG00000012714

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PRDX1
• Ensembl ID: ENSMODG00000002382
• Aliases: None
• Description: peroxiredoxin 1 [Source:HGNC Symbol;Acc:9352]

Sequence

>retro_mdom_555
ATTGGGTATCAGGCCTCTACTTTCAAAGTTATAGCTGCTATGACATCTGGGAAGTTCAAAGATATCAACCTTTTTAACTA
CAAAGGGAAATATCTTATGTTCTTTTCTTACCTCTTGTACATCACCTTGTATGTCCCACAGAGATTACAGTATTCATTCA
ATCATCAAGGTTAAGAATTGAAGAAACTTTACTGCCAAGTAGCTAGTGCTTCAGGAGCCTCATACTTTGGTCACCCTGCC
CGGGTCAACACATCCAAGAAGCAAGGTAGACTGAAAGTCACGAATACACCATTAATAGCTGACCACAAATATTCCATTGC
TAAGAATTATGGAGTCCAAAAGGCATATGAGGGAAGTTCATTCAAGAGTCTCTTCATCACTGATGAAAAGAGGATCCTTC
ACCAGATCACCATCAATGACTTTCCTTTGGGCCACTTTGTGGATGAGGCACTGTACCTAGTCCAGGACTTCCAGTTCATA
GGCAAGAATGGCAAAATGTGCCCACTGGCTGGAAA

Alignment

ORF - retro_mdom_555 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 52.02 %
• Parental protein coverage: 85.93 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  IGRPAPNFRATAVMPDQQFKDISLSDYRGKYVVLFFYPLDFTFVCPTEI-IAFSDRAEEFKKLNCQVIGA
          IG..A..F...A.M....FKDI.L..Y.GKY...F.Y.L..T...P......F.....E.KKL.CQV..A
Retrocopy IGYQASTFKVIAAMTSGKFKDINLFNYKGKYLMFFSYLLYITLYVPQRLQYSFNHQG*ELKKLYCQVASA

Parental  SVDSHFCHLAWVNTVKKQGGLGPVNIPLVSDAKRTIAQDYGVLKADEGISFRGLFIIDEKGILRQITIND
          S..S.F.H.A.VNT.KKQG.L...N.PL..D.K..IA..YGV.KA.EG.SF..LFI.DEK.IL.QITIND
Retrocopy SGASYFGHPARVNTSKKQGRLKVTNTPLIADHKYSIAKNYGVQKAYEGSSFKSLFITDEKRILHQITIND

Parental  LPVGRSVDETLRLIQAFQFTDKYGEVC-PAGWK
          .P.G..VDE.L.L.Q.FQF..K.G..C.P.GWK
Retrocopy FPLGHFVDEALYLVQDFQFIGKNGKMC<PTGWK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.39 RPM	0.00 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_555 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_555 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 32 parental genes, and 86 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000013632	2 retrocopies	retro_amel_1116, retro_amel_539,
Bos taurus	ENSBTAG00000003642	2 retrocopies	retro_btau_1299, retro_btau_1446,
Canis familiaris	ENSCAFG00000004567	5 retrocopies	retro_cfam_1313, retro_cfam_270, retro_cfam_577, retro_cfam_834, retro_cfam_988,
Choloepus hoffmanni	ENSCHOG00000003358	5 retrocopies	retro_chof_1140, retro_chof_134, retro_chof_1714, retro_chof_2035, retro_chof_2450,
Ciona intestinalis	ENSCING00000003002	1 retrocopy	retro_cint_8,
Callithrix jacchus	ENSCJAG00000004807	2 retrocopies	retro_cjac_1201, retro_cjac_2884,
Cavia porcellus	ENSCPOG00000014137	3 retrocopies	retro_cpor_1079, retro_cpor_290, retro_cpor_398,
Dasypus novemcinctus	ENSDNOG00000018488	1 retrocopy	retro_dnov_2071,
Dipodomys ordii	ENSDORG00000008975	1 retrocopy	retro_dord_727,
Equus caballus	ENSECAG00000008678	1 retrocopy	retro_ecab_81,
Echinops telfairi	ENSETEG00000007922	11 retrocopies	retro_etel_112, retro_etel_1157, retro_etel_1245, retro_etel_1442, retro_etel_1838, retro_etel_2121, retro_etel_2122, retro_etel_308, retro_etel_367, retro_etel_460, retro_etel_556,
Felis catus	ENSFCAG00000028484	1 retrocopy	retro_fcat_1714,
Homo sapiens	ENSG00000117450	1 retrocopy	retro_hsap_4230,
Macropus eugenii	ENSMEUG00000006820	4 retrocopies	retro_meug_1694, retro_meug_1711, retro_meug_2059, retro_meug_662,
Macaca mulatta	ENSMMUG00000006221	1 retrocopy	retro_mmul_762,
Monodelphis domestica	ENSMODG00000002382	2 retrocopies	retro_mdom_1787, retro_mdom_555 ,
Monodelphis domestica	ENSMODG00000006978	1 retrocopy	retro_mdom_1770,
Monodelphis domestica	ENSMODG00000009286	1 retrocopy	retro_mdom_1062,
Mus musculus	ENSMUSG00000028691	5 retrocopies	retro_mmus_1466, retro_mmus_1659, retro_mmus_1786, retro_mmus_3129, retro_mmus_3167,
Nomascus leucogenys	ENSNLEG00000014524	2 retrocopies	retro_nleu_1040, retro_nleu_1627,
Oryctolagus cuniculus	ENSOCUG00000005951	2 retrocopies	retro_ocun_1064, retro_ocun_1124,
Otolemur garnettii	ENSOGAG00000002303	4 retrocopies	retro_ogar_1219, retro_ogar_1333, retro_ogar_1588, retro_ogar_486,
Pongo abelii	ENSPPYG00000001411	1 retrocopy	retro_pabe_3409,
Pan troglodytes	ENSPTRG00000000675	1 retrocopy	retro_ptro_2874,
Pteropus vampyrus	ENSPVAG00000015001	1 retrocopy	retro_pvam_179,
Rattus norvegicus	ENSRNOG00000017194	8 retrocopies	retro_rnor_1401, retro_rnor_1488, retro_rnor_1574, retro_rnor_1656, retro_rnor_1736, retro_rnor_2063, retro_rnor_2292, retro_rnor_2401,
Sorex araneus	ENSSARG00000004703	5 retrocopies	retro_sara_153, retro_sara_370, retro_sara_399, retro_sara_633, retro_sara_95,
Sus scrofa	ENSSSCG00000003914	1 retrocopy	retro_sscr_719,
Ictidomys tridecemlineatus	ENSSTOG00000023413	2 retrocopies	retro_itri_631, retro_itri_817,
Tupaia belangeri	ENSTBEG00000015997	4 retrocopies	retro_tbel_3922, retro_tbel_4017, retro_tbel_4024, retro_tbel_4669,
Tarsius syrichta	ENSTSYG00000011031	1 retrocopy	retro_tsyr_1781,
Tursiops truncatus	ENSTTRG00000008858	4 retrocopies	retro_ttru_1350, retro_ttru_1878, retro_ttru_234, retro_ttru_36,