RetrogeneDB ID: retro_ggor_889

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 12:87144210..87145126(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000024578
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: FAM114A2
• Ensembl ID: ENSGGOG00000007198
• Aliases: None
• Description: None

Sequence

>retro_ggor_889
CTGATGAACCGAAATGCTACACTATCCCAGGTTTTACGAGAGGCGAAGGAGAAAGAAGAGATACGGGCCTCCAATGAGGT
TACCGTGGAAACAGACAAGAAAACTCATTATGGGCTACTCTTTGATGAATTTCAAGGCCTTTCACATCTAGAAGCTCTGG
AGATGCTTTCCCGAGAAAGTGAAATAAAGGTGAAATCTATCCTTAATTCTCTGAGTGGAGAAGAATTAGAGACTCTAAAA
GTTGAATTAGAGCAACTCAAAGAAGCATTTTCTCTAGCAGAATTTTGTGAAGAAGAGGAAGAAGAGAAAAAAGGGGATGA
AGATTTTACCAAGGACATAACAGAGCTGTTTTCCCAGCTGCACGTTTCCTCCAAACCAGAGAAACTTGCCAGGGCAAGAA
ACACCGCCCACGAATGGATCAGGAAGTCTCTGACCAAGCCATTAGCAGAGAATGAAGAAGGAGAAAAACAGTCGGAAGCA
GAAAATACTGAGCAAGTCAACAAAAATTCAATAGAGGATATCCATGCGTTTGCAATCCGGAGCCTGGCTGAACTGACTGC
CGGCTCAATTGAACTATTCCACAAAACAGCTGCATTGGTTCTGCATGGCAGGAAGCAGGAAGTGACAGCCATAGAAAGGA
GCCAAACTCTTTCCCAGATGACAATTGTGTTGTGTAAAGAGTTGTCCTCTCTGTCTAAAGAGTTCACCACCTGCCTAACA
ACTGCTGGGGTCAAAGAAATGGCAGATGTCCTTAACCCATTAATCACTGCAGTATTTCTAGAGGCATCAAACAGTGCCTC
CTACATCCAGGACGCCTTTCAGCTACTCTTAACCTGTGCTAGAGATCTCTCTCATTGAGAACAAGATTGAATCACACAGG
CATGAGCTGCAGGGCCAGAAACCTTTGTTAGAACAT

Alignment

ORF - retro_ggor_889 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 98.69 %
• Parental protein coverage: 59.69 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  LMNRNATLSQVLREAKEKEEIRTSNEVTVETDKKTHYGLLFDEFQGLSHLEALEMLSRESEIKVKSILNS
          LMNRNATLSQVLREAKEKEEIR.SNEVTVETDKKTHYGLLFDEFQGLSHLEALEMLSRESEIKVKSILNS
Retrocopy LMNRNATLSQVLREAKEKEEIRASNEVTVETDKKTHYGLLFDEFQGLSHLEALEMLSRESEIKVKSILNS

Parental  LSGEELETLKVELEQLKEAFSLAEFCEEEEEEKKGDEDFTKDITELFSQLHVSSKPEKLARARNTTHEWI
          LSGEELETLKVELEQLKEAFSLAEFCEEEEEEKKGDEDFTKDITELFSQLHVSSKPEKLARARNT.HEWI
Retrocopy LSGEELETLKVELEQLKEAFSLAEFCEEEEEEKKGDEDFTKDITELFSQLHVSSKPEKLARARNTAHEWI

Parental  RKSLTKPLAENEEGEKQSEAENTEQVNKNSIEDIHAFAIRSLAELTACSIELFHKTAALVLHGRKQEVTA
          RKSLTKPLAENEEGEKQSEAENTEQVNKNSIEDIHAFAIRSLAELTA.SIELFHKTAALVLHGRKQEVTA
Retrocopy RKSLTKPLAENEEGEKQSEAENTEQVNKNSIEDIHAFAIRSLAELTAGSIELFHKTAALVLHGRKQEVTA

Parental  IERSQTLSQMTIVLCKELSSLSKEFTTCLTTAGVKEMADVLNPLITAVFLEASNSASYIQDAFQLLL-PV
          IERSQTLSQMTIVLCKELSSLSKEFTTCLTTAGVKEMADVLNPLITAVFLEASNSASYIQDAFQLLL.PV
Retrocopy IERSQTLSQMTIVLCKELSSLSKEFTTCLTTAGVKEMADVLNPLITAVFLEASNSASYIQDAFQLLL>PV

Parental  LEISLIENKIESHRHELQGQKPLLEH
          LEISLIENKIESHRHELQGQKPLLEH
Retrocopy LEISLIENKIESHRHELQGQKPLLEH

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.34 RPM	3.64 RPM
SRP007412_cerebellum	0.16 RPM	2.99 RPM
SRP007412_heart	0.06 RPM	1.41 RPM
SRP007412_kidney	0.57 RPM	7.97 RPM
SRP007412_liver	0.34 RPM	5.09 RPM
SRP007412_testis	3.94 RPM	31.39 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_889 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_889 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 3 parental genes, and 3 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000017653	1 retrocopy	retro_cfam_975,
Gorilla gorilla	ENSGGOG00000007198	1 retrocopy	retro_ggor_889 ,
Tupaia belangeri	ENSTBEG00000004757	1 retrocopy	retro_tbel_3070,