RetrogeneDB ID: retro_ggor_669

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 11:99101007..99101915(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: KIAA1191
• Ensembl ID: ENSGGOG00000023834
• Aliases: None
• Description: None

Sequence

>retro_ggor_669
ATGGCTTCAAGACAACCAGAAGTGCCTGCTCTTGAGGCTAGTGGGCCTCTAGGCAAGATGTTCCTGCCCACCAGGATATA
CCACTGGGCCAGCTACGATGATGCCCTCAAGGACCCTGCGCCCATGACTCTTCCTCCATCGGACATGGGCAGTGTCCCCT
GGAAGCCAGTGATTCCAGAGCACAATATCAGTGCATCACCAAGGTGGAGGAAGATGAGGCCAGCCTACCCTCCCCAGCCA
TGACCCTGTCATCGGCCATTGACAGTGTGGACAAGGTCCCAGTGGTGAAGGCTAAGCTACACATGTCATCATGAATTATC
GGATCACAAAACAGACCCAGGAAAGTATTCAGCATTTTGGGTGACAGGCAGGGCTGAGAGATGCTGGCTACACACCCCAC
AGGGGCCTCACCACCGAGGAGACCAAGTACCTTCCAGTGGCAGGAGCACTCCACAGACTAAAGCTACAGAGGAGAGAGAT
AACAAAAGAATAGAGGCAGCCTGCATCAGCCCAGTCGCCTCAAGCTCCACTCCTCATTCTTCCCCTAAGCAGAAGCCCAG
AGGCTGGCTCACTTCTGGTTCTTCCACAGCTTTACCTGGCCCAAATCCTAGCACCATGGATTCTGGAAGTGGGGATAAAG
ACAGAAACTTGTCAGGTAAGTGGAGCCTCTTTGGACCAAGATGCCTTCAGAAGTATGATTCTGGAAGTTTTGCCACCCAG
GCCTACAAGGAGCCTAGAAGCCTTCTCCAATGGAATTGATCCATGCCCAGGCCAACTGAATGGCTGAAGATCCAGTAACC
TTGAAGCTGCCCAAGATGAACATCCTAGTGATGGAAGGGAAGAAACAGCCACCATGGACCCATAAGCTCAAACCGCCTGA
CTTGAATGTGCTCATACCCACCGGCTTC

Alignment

ORF - retro_ggor_669 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.85 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  MASRQPEVPALEASAPLGKMSLPIGIYRRALSYDDTLEDPAPMTPPPSDMGSVPWKPVIPER-KYQHLAK
          MASRQPEVPALEAS.PLGKM.LP..IY..A.SYDD.L.DPAPMT.PPSDMGSVPWKPVIPE...YQ...K
Retrocopy MASRQPEVPALEASGPLGKMFLPTRIYHWA-SYDDALKDPAPMTLPPSDMGSVPWKPVIPEH<QYQCITK

Parental  VEEGEASLPSPAMTLSSAIDSVDKVPVVKAK-ATHVIMNSLITKQTQESIQHFERQAGLRDAGYTPHKGL
          VEE.EASLPSPAMTLSSAIDSVDKVPVVKAK.ATHVIMN..ITKQTQESIQHF..QAGLRDAGYTPH.GL
Retrocopy VEEDEASLPSPAMTLSSAIDSVDKVPVVKAK<ATHVIMNYRITKQTQESIQHFG*QAGLRDAGYTPHRGL

Parental  TTEETKYLRVAEALHKLKLQSGEITKEERQPASAQS-TPSTTPHSSPKQRPRGWFTSGSSTALPGPNPST
          TTEETKYL.VA.ALH.LKLQ..EITKE.RQPASAQS...S.TPHSSPKQ.PRGW.TSGSSTALPGPNPST
Retrocopy TTEETKYLPVAGALHRLKLQRREITKE*RQPASAQS<ASSSTPHSSPKQKPRGWLTSGSSTALPGPNPST

Parental  MDSGSGDKDRNLSDKWSLFGPRSLQKYDSGSFATQAYR-GAQKPSPLELIGAQANRMAEDPAALKPPKMD
          MDSGSGDKDRNLS.KWSLFGPR.LQKYDSGSFATQAY..GA.KPSP.ELI.AQAN.MAEDP..LK.PKM.
Retrocopy MDSGSGDKDRNLSGKWSLFGPRCLQKYDSGSFATQAYK<GA*KPSPMELIHAQAN*MAEDPVTLKLPKMN

Parental  IPVMEGKKQPPRAHNLKPRDLNVLTPTGF
          I.VMEGKKQPP..H.LKP.DLNVL.PTGF
Retrocopy ILVMEGKKQPPWTHKLKPPDLNVLIPTGF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.19 RPM	72.70 RPM
SRP007412_cerebellum	0.00 RPM	65.52 RPM
SRP007412_heart	0.03 RPM	10.98 RPM
SRP007412_kidney	0.00 RPM	233.48 RPM
SRP007412_liver	0.00 RPM	29.39 RPM
SRP007412_testis	0.10 RPM	21.45 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_669 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_669 has 5 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_817
Pan troglodytes	retro_ptro_568
Pongo abelii	retro_pabe_729
Macaca mulatta	retro_mmul_1082
Callithrix jacchus	retro_cjac_901

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Parental genes homology:

Parental genes homology involve 25 parental genes, and 64 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000006123	4 retrocopies	retro_chof_1411, retro_chof_1751, retro_chof_2197, retro_chof_959,
Callithrix jacchus	ENSCJAG00000012337	2 retrocopies	retro_cjac_1699, retro_cjac_901,
Cavia porcellus	ENSCPOG00000019402	1 retrocopy	retro_cpor_625,
Dasypus novemcinctus	ENSDNOG00000002676	3 retrocopies	retro_dnov_2220, retro_dnov_753, retro_dnov_976,
Equus caballus	ENSECAG00000003238	1 retrocopy	retro_ecab_621,
Felis catus	ENSFCAG00000007189	1 retrocopy	retro_fcat_1625,
Homo sapiens	ENSG00000122203	4 retrocopies	retro_hsap_1641, retro_hsap_3089, retro_hsap_524, retro_hsap_817,
Gorilla gorilla	ENSGGOG00000023834	4 retrocopies	retro_ggor_1240, retro_ggor_2122, retro_ggor_482, retro_ggor_669 ,
Loxodonta africana	ENSLAFG00000028878	1 retrocopy	retro_lafr_313,
Myotis lucifugus	ENSMLUG00000003498	1 retrocopy	retro_mluc_667,
Macaca mulatta	ENSMMUG00000003921	3 retrocopies	retro_mmul_1082, retro_mmul_1566, retro_mmul_1971,
Monodelphis domestica	ENSMODG00000005274	6 retrocopies	retro_mdom_116, retro_mdom_1992, retro_mdom_218, retro_mdom_56, retro_mdom_722, retro_mdom_751,
Mustela putorius furo	ENSMPUG00000012579	1 retrocopy	retro_mputfur_1237,
Mus musculus	ENSMUSG00000025871	2 retrocopies	retro_mmus_1580, retro_mmus_737,
Nomascus leucogenys	ENSNLEG00000012473	4 retrocopies	retro_nleu_1327, retro_nleu_2233, retro_nleu_251, retro_nleu_2578,
Oryctolagus cuniculus	ENSOCUG00000012191	3 retrocopies	retro_ocun_1263, retro_ocun_1415, retro_ocun_1509,
Otolemur garnettii	ENSOGAG00000008281	6 retrocopies	retro_ogar_1543, retro_ogar_1986, retro_ogar_2289, retro_ogar_3002, retro_ogar_3075, retro_ogar_781,
Procavia capensis	ENSPCAG00000008839	1 retrocopy	retro_pcap_277,
Pongo abelii	ENSPPYG00000016068	4 retrocopies	retro_pabe_223, retro_pabe_2558, retro_pabe_2615, retro_pabe_729,
Pan troglodytes	ENSPTRG00000017558	5 retrocopies	retro_ptro_1111, retro_ptro_2086, retro_ptro_2975, retro_ptro_392, retro_ptro_568,
Pteropus vampyrus	ENSPVAG00000012448	1 retrocopy	retro_pvam_118,
Rattus norvegicus	ENSRNOG00000017133	2 retrocopies	retro_rnor_968, retro_rnor_969,
Ictidomys tridecemlineatus	ENSSTOG00000000946	2 retrocopies	retro_itri_1163, retro_itri_960,
Tupaia belangeri	ENSTBEG00000013189	1 retrocopy	retro_tbel_2271,
Tursiops truncatus	ENSTTRG00000005376	1 retrocopy	retro_ttru_383,